Steve R Makkar
Overview
Explore the profile of Steve R Makkar including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
436
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Recent Articles
1.
Makkar S, Hansen K, Hotaling N, Toler A, Sidky H
Open Forum Infect Dis
. 2025 Mar;
12(2):ofae740.
PMID: 40041442
Background: We applied a target trial emulation framework to estimate the association between early and delayed initiation of remdesivir (RDV) with mortality in hospitalized adults between May 1, 2020, and...
2.
Hansen K, Makkar S, Sahner D, Fessel J, Hotaling N, Sidky H
medRxiv
. 2023 Jul;
PMID: 37398261
Importance: COVID-19 has placed a monumental burden on the health care system globally. Although no longer a public health emergency, there is still a pressing need for effective treatments to...
3.
Leung Y, Barzilai N, Batko-Szwaczka A, Beker N, Boerner K, Brayne C, et al.
Alzheimers Dement
. 2022 Dec;
19(6):2265-2275.
PMID: 36453627
Introduction: There are limited data on prevalence of dementia in centenarians and near-centenarians (C/NC), its determinants, and whether the risk of dementia continues to rise beyond 100. Methods: Participant-level data...
4.
Koncz R, Wen W, Makkar S, Lam B, Crawford J, Rowe C, et al.
J Alzheimers Dis
. 2022 Feb;
86(4):1617-1628.
PMID: 35213365
Background: Cerebral small vessel disease (SVD) and Alzheimer's disease pathology, namely amyloid-β (Aβ) deposition, commonly co-occur. Exactly how they interact remains uncertain. Objective: Using participants from the Alzheimer's Disease Neuroimaging...
5.
Makkar S, Lipnicki D, Crawford J, Kochan N, Castro-Costa E, Lima-Costa M, et al.
Arch Gerontol Geriatr
. 2020 Aug;
91:104112.
PMID: 32738518
Background: We examined how the relationship between education and latelife cognitive impairment (defined as a Mini Mental State Examination score below 24) is influenced by age, sex, ethnicity, and Apolipoprotein...
6.
Makkar S, Lipnicki D, Crawford J, Kochan N, Castro-Costa E, Lima-Costa M, et al.
J Gerontol A Biol Sci Med Sci
. 2020 May;
75(10):1863-1873.
PMID: 32396611
We aimed to examine the relationship between Apolipoprotein E ε4 (APOE*4) carriage on cognitive decline, and whether these associations were moderated by sex, baseline age, ethnicity, and vascular risk factors....
7.
Samaras K, Makkar S, Crawford J, Kochan N, Slavin M, Wen W, et al.
J Am Coll Cardiol
. 2019 Nov;
74(21):2554-2568.
PMID: 31753200
Background: There is widespread consumer concern that statin use may be associated with impaired memory and cognitive decline. Objectives: This study sought to examine the association between statin use and...
8.
Maasakkers C, Claassen J, Gardiner P, Olde Rikkert M, Lipnicki D, Scarmeas N, et al.
Sports Med
. 2019 Sep;
50(2):403-413.
PMID: 31529300
Background: Besides physical activity as a target for dementia prevention, sedentary behaviour is hypothesized to be a potential target in its own right. The rising number of persons with dementia...
9.
Lennon M, Makkar S, Crawford J, Sachdev P
J Alzheimers Dis
. 2019 Aug;
71(1):307-316.
PMID: 31381518
Background: Hypertension is an established risk factor for stroke and vascular dementia but recent meta-analyses examining the association between Alzheimer's disease (AD) and hypertension have found no significant association. These...
10.
Lipnicki D, Makkar S, Crawford J, Thalamuthu A, Kochan N, Lima-Costa M, et al.
PLoS Med
. 2019 Jul;
16(7):e1002853.
PMID: 31335910
Background: With no effective treatments for cognitive decline or dementia, improving the evidence base for modifiable risk factors is a research priority. This study investigated associations between risk factors and...