Steve D Thomas
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Explore the profile of Steve D Thomas including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
130
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Recent Articles
1.
Teo S, Denny K, Stirling D, Thomas S, Morseth S, Hoberman A
Toxicol Sci
. 2004 Jul;
81(2):379-89.
PMID: 15229368
The present study determined effects of thalidomide on three successive generations of New Zealand White rabbits after oral dosing to F0 maternal rabbits during the later third of gestation (post...
2.
Teo S, Colburn W, Tracewell W, Kook K, Stirling D, Jaworsky M, et al.
Clin Pharmacokinet
. 2004 Apr;
43(5):311-27.
PMID: 15080764
Thalidomide is a racemic glutamic acid derivative approved in the US for erythema nodosum leprosum, a complication of leprosy. In addition, its use in various inflammatory and oncologic conditions is...
3.
Teo S, Denny K, Stirling D, Thomas S, Morseth S, Hoberman A
Birth Defects Res B Dev Reprod Toxicol
. 2004 Mar;
71(1):1-16.
PMID: 14991906
Background: The present work was performed to determine the effect of thalidomide exposure on reproductive function and early embryonic development. Methods: Twenty-five female New Zealand White rabbits were orally gavaged...
4.
Teo S, Scheffler M, Wu A, Stirling D, Thomas S, Stypinski D, et al.
J Clin Pharmacol
. 2004 Jan;
44(2):173-8.
PMID: 14747426
Attention deficit hyperactivity disorder (ADHD) in children is effectively treated by racemic oral methylphenidate (dl-MPH). The d-isomer (d-MPH) has been developed as an improved treatment for ADHD since only half...
5.
Teo S, Stirling D, Hoberman A, Christian M, Thomas S, Khetani V
Birth Defects Res B Dev Reprod Toxicol
. 2003 Jul;
68(2):162-71.
PMID: 12866707
Background: D,L-threo-Methylphenidate (D,L-MPH) is marketed currently for attention deficit hyperactivity disorder in children. D-threo-methylphenidate (dexmethylphenidate; D-MPH) is a refined formulation of D,L-methylphenidate containing only the active enantiomer and was recently...
6.
Teo S, Stirling D, Thomas S, Evans M, Khetani V
Int J Toxicol
. 2003 Jul;
22(3):215-26.
PMID: 12851154
d-Methylphenidate (d-MPH) was approved as a treatment for attention deficit hyperactivity disorder (ADHD) in children. The repeated-dose toxicity of the d enantiomer of d,l-methylphenidate (d,l-MPH) was assessed in male and...
7.
Teo S, San R, Wagner V, Gudi R, Stirling D, Thomas S, et al.
Mutat Res
. 2003 May;
537(1):67-79.
PMID: 12742508
D-Methylphenidate (dexmethylphenidate; D-MPH) and its racemate D,L-methylphenidate (D,L-MPH) are currently prescribed for the chronic treatment of attention deficit hyperactivity disorder (ADHD) in children. Studies have shown that D-MPH is the...
8.
Teo S, Chen Y, Muller G, Chen R, Thomas S, Stirling D, et al.
Chirality
. 2003 Apr;
15(4):348-51.
PMID: 12666243
CC-4047 is a racemic second-generation immunomodulatory drug currently in clinical development for various oncologic indications. It has potent effects on key cytokines including tumor necrosis factor-alpha, interleukin (IL-10), and interferon...
9.
Teo S, Stirling D, Thomas S, Khetani V
Pharmacol Biochem Behav
. 2003 Jan;
74(3):747-54.
PMID: 12543241
D,L-methylphenidate (Ritalin) is used to treat attention deficit hyperactivity disorder (ADHD) in children. The therapeutic effect is predominantly due to the d enantiomer. Dexmethylphenidate (D-MPH; Focalin) was therefore developed for...
10.
Teo S, Resztak K, Scheffler M, Kook K, Zeldis J, Stirling D, et al.
Microbes Infect
. 2002 Oct;
4(11):1193-202.
PMID: 12361920
Leprosy is a chronic infection of the skin and nerves caused by Mycobacterium leprae. Erythema nodosum leprosum (ENL) is a reactive state in lepromatous leprosy. Thalidomide has been used to...