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Stephen Y Lai

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Articles 232
Citations 5319
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Recent Articles
1.
Vargas L, Langlie J, McGee C, Ma R, Perdigon O, Lai S, et al.
J Otolaryngol Head Neck Surg . 2025 Mar; 54:19160216251321457. PMID: 40071635
ImportanceSelective, modified radical, and radical neck dissections are common surgical procedures that can result in significant musculoskeletal issues of the neck and shoulder. Quality-of-life evaluations after neck dissection must assess...
2.
Houl J, Bagheri-Yarmand R, Kunnimalaiyaan M, Miranda Mendez P, Kidd J, Dadbin A, et al.
bioRxiv . 2025 Mar; PMID: 40027641
Patients with poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) face a much poorer prognosis than those with differentiated thyroid cancers. Around 25% of PDTCs and 35% of...
3.
Rigert J, Kaffey Z, Belal Z, Tripuraneni L, Humbert-Vidan L, Sahli A, et al.
medRxiv . 2025 Feb; PMID: 39974112
Objective: Osteoradionecrosis of the jaw (ORNJ) is a chronic radiation-associated toxicity that lacks standardized classification criteria and treatment guidelines. Understanding early signs of tissue injury could help us better predict,...
4.
McMillan H, Warneke C, Buoy S, Porsche C, Savage K, Lai S, et al.
JAMA Otolaryngol Head Neck Surg . 2025 Feb; PMID: 39913160
Importance: Late radiation-associated dysphagia (RAD) after head and neck cancer (HNC) treatment is challenging and commonly treatment refractory, with fibrosis stiffening connective tissues and compressing peripheral nerve tracts, contributing to...
5.
Moreno A, Watson E, Humbert-Vidan L, Peterson D, van Dijk L, Urbano T, et al.
Int J Radiat Oncol Biol Phys . 2025 Jan; PMID: 39826846
Purpose: Osteoradionecrosis of the jaw (ORNJ) is a severe iatrogenic disease characterized by bone death after radiation therapy (RT) to the head and neck. With over 9 published definitions and...
6.
Mao S, Wang J, McMillan H, Mohamed A, Buoy S, Ahmed S, et al.
Head Neck . 2025 Jan; PMID: 39794912
Background: Quantifying head and neck lymphedema and fibrosis (HN-LEF) is crucial in the investigation and management of treatment sequelae in head and neck cancer (HNC). Methods: The T1- and T2-weighted...
7.
Stricker E, Peckham-Gregory E, Lai S, Sandulache V, Scheurer M
Microorganisms . 2025 Jan; 12(12. PMID: 39770638
Papillary thyroid cancer (PTC) is one of the fastest-growing cancers worldwide, lacking established causal factors or validated early diagnostics. Human endogenous retroviruses (HERVs), comprising 8% of human genomes, have potential...
8.
Wahid K, Dede C, El-Habashy D, Kamel S, Rooney M, Khamis Y, et al.
ArXiv . 2024 Dec; PMID: 39650598
Magnetic resonance (MR)-guided radiation therapy (RT) is enhancing head and neck cancer (HNC) treatment through superior soft tissue contrast and longitudinal imaging capabilities. However, manual tumor segmentation remains a significant...
9.
Sehl O, Guo K, Mohtasebzadeh A, Kim P, Fellows B, Weyhmiller M, et al.
Radiol Adv . 2024 Nov; 1(3):umae024. PMID: 39574515
Background: Sentinel lymph node biopsy (SLNB) is an important cancer diagnostic staging procedure. Conventional SLNB procedures with Tc radiotracers and scintigraphy are constrained by tracer half-life and, in some cases,...
10.
Kamel S, Humbert-Vidan L, Kaffey Z, Abusaif A, Fuentes D, Wahid K, et al.
medRxiv . 2024 Sep; PMID: 39314948
Purpose: This study aims to identify radiomic features extracted from contrast-enhanced CT scans that differentiate osteoradionecrosis (ORN) from normal mandibular bone in patients with head and neck cancer (HNC) treated...