Stephen W Edwards
Overview
Explore the profile of Stephen W Edwards including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
46
Citations
921
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0
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Recent Articles
11.
Sullivan K, Allen D, Clippinger A, Wilson D, Edwards S, Glover K, et al.
ALTEX
. 2021 Jan;
38(2):327-335.
PMID: 33511999
Efforts are underway to develop and implement nonanimal approaches which can characterize acute systemic lethality. A workshop was held in October 2019 to discuss developments in the prediction of acute...
12.
Whaley P, Edwards S, Kraft A, Nyhan K, Shapiro A, Watford S, et al.
Environ Health Perspect
. 2020 Dec;
128(12):125001.
PMID: 33356525
Background: Although the implementation of systematic review and evidence mapping methods stands to improve the transparency and accuracy of chemical assessments, they also accentuate the challenges that assessors face in...
13.
Pan H, Edwards S, Ives C, Covert H, Harville E, Lichtveld M, et al.
Curr Opin Toxicol
. 2020 May;
16:75-82.
PMID: 32457927
Research consortia play a key role in our understanding of how environmental exposures influence health and wellbeing, especially in the case of catastrophic events such as the Deepwater Horizon oil...
14.
Allen T, Nelms M, Edwards S, Goodman J, Gutsell S, Russell P
Environ Sci Technol
. 2020 May;
54(12):7461-7470.
PMID: 32432465
Molecular initiating events (MIEs) are key events in adverse outcome pathways that link molecular chemistry to target biology. As they are based on chemistry, these interactions are excellent targets for...
15.
Ankley G, Edwards S
Curr Opin Toxicol
. 2018 Apr;
9:1-7.
PMID: 29682628
The adverse outcome pathway (AOP) framework serves as a knowledge assembly, interpretation, and communication tool designed to support the translation of pathway-specific mechanistic data into responses relevant to assessing and...
16.
Fay K, Villeneuve D, Swintek J, Edwards S, Nelms M, Blackwell B, et al.
Toxicol Sci
. 2018 Mar;
163(2):500-515.
PMID: 29529260
The U.S. Environmental Protection Agency's ToxCast program has screened thousands of chemicals for biological activity, primarily using high-throughput in vitro bioassays. Adverse outcome pathways (AOPs) offer a means to link...
17.
Pittman M, Edwards S, Ives C, Mortensen H
Toxicol Appl Pharmacol
. 2018 Feb;
343:71-83.
PMID: 29454060
The Adverse Outcome Pathway (AOP) framework describes the progression of a toxicity pathway from molecular perturbation to population-level outcome in a series of measurable, mechanistic responses. The controlled, computer-readable vocabulary...
18.
Hines D, Edwards S, Conolly R, Jarabek A
Environ Sci Technol
. 2017 Dec;
52(2):839-849.
PMID: 29236470
Cumulative risk assessment (CRA) methods promote the use of a conceptual site model (CSM) to apportion exposures and integrate risk from multiple stressors. While CSMs may encompass multiple species, evaluating...
19.
Hill 3rd T, Nelms M, Edwards S, Martin M, Judson R, Corton J, et al.
Toxicol Sci
. 2016 Sep;
155(1):157-169.
PMID: 27679563
Recent international efforts have led to proposals for modified carcinogenicity testing paradigms based on data from shorter-term studies. The main goal of the current study was to evaluate the negative...
20.
Teeguarden J, Tan Y, Edwards S, Leonard J, Anderson K, Corley R, et al.
Environ Sci Technol
. 2016 Aug;
50(17):8921-2.
PMID: 27509267
No abstract available.