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Stephen Tong

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Articles 230
Citations 2490
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Recent Articles
1.
Kupka E, Hesselman S, Gunnarsdottir J, Wikstrom A, Cluver C, Tong S, et al.
JAMA Netw Open . 2025 Feb; 8(2):e2457828. PMID: 39899294
Importance: It is unclear whether a higher dose (150-160 mg) or a lower dose (75 mg) of aspirin should be used to prevent preeclampsia. Objectives: To compare the risk of...
2.
Wong G, Hartmann S, Nonn O, Cannon P, Nguyen T, Kandel M, et al.
Stem Cell Rev Rep . 2024 Dec; PMID: 39688759
Leucine-rich repeat-containing G protein-coupled receptors 5/4 (LGR5/LGR4) are critical stem cell markers in epithelial tissues including intestine. They agonise wingless-related integration site (WNT) signalling. Until now, LGR5/LGR4 were uncharacterised in...
3.
Palm K, Cluver C, Langenegger E, Tong S, Walker S, Imberg H, et al.
Pregnancy Hypertens . 2024 Nov; 38:101168. PMID: 39577064
Objectives: To assess whether plasma concentrations of the circulating inflammatory proteins Interleukin-6 (IL-6), Vascular Cell Adhesion Molecule-1 (VCAM-1) and C-Reactive Protein (CRP) are increased in women with preeclampsia with end-organ...
4.
Bergman L, Hannsberger D, Schell S, Imberg H, Langenegger E, Moodley A, et al.
Am J Obstet Gynecol . 2024 Nov; PMID: 39486498
Background: Eclampsia is a serious pregnancy complication and is associated with cerebral edema and infarctions. However, the underlying pathophysiology of eclampsia remains poorly explored. Objective: This study aimed to assess...
5.
Nonn O, Debnath O, Valdes D, Sallinger K, Secener A, Fischer C, et al.
Hypertension . 2024 Oct; PMID: 39440423
Background: Preeclampsia is a severe hypertensive disorder in pregnancy that causes preterm delivery, maternal and fetal morbidity, mortality, and life-long sequelae. Understanding the pathogenesis of preeclampsia is a critical first...
6.
Gordon H, Salim N, Tong S, Walker S, De Silva M, Cluver C, et al.
BMC Med . 2024 Sep; 22(1):418. PMID: 39334302
Background: Metformin is a hypoglycaemic medication that has been proposed to treat or prevent preeclampsia. Combining national birth data from Scotland and Sweden, we investigated whether metformin used during pregnancy...
7.
Bartho L, Walker S, Cannon P, Nguyen T, Nguyen A, Botha S, et al.
Placenta . 2024 Aug; 156:10-13. PMID: 39216164
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) is an inhibitory receptor expressed on immune cells. We evaluated LAIR1 in placentas from preeclamptic or small for gestational age (SGA) pregnancies, and placental explant...
8.
Wong G, Hartmann S, Simmons D, Ellis S, Nonn O, Cannon P, et al.
Stem Cell Rev Rep . 2024 Jul; 20(7):1954-1970. PMID: 39028417
Dysregulated progenitor cell populations may contribute to poor placental development and placental insufficiency pathogenesis. Side-population cells possess progenitor properties. Recent human trophoblast side-population isolation identified enrichment of 8 specific genes...
9.
Bartho L, McKeating D, Walker S, Nijagal B, MacDonald T, Pritchard N, et al.
Sci Rep . 2024 Jul; 14(1):15829. PMID: 38982217
Metabolomics is the study of small molecules (metabolites), within cells, tissues and biofluids. Maternal metabolites can provide important insight into the health and development of both mother and fetus throughout...
10.
Cluver C, Bergman L, Imberg H, Mol B, Hall D, Bekker A, et al.
BMJ Open . 2024 Jun; 14(6):e082880. PMID: 38890136
Introduction: Preterm pre-eclampsia is a leading cause of maternal morbidity and mortality. The Pre-eclampsia Intervention 2 (PI 2) trial suggested that metformin sustained release (XR) may prolong gestation by a...