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Stephen Thein

Explore the profile of Stephen Thein including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 276
Followers 0
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Recent Articles
1.
Kunz D, Dauvilliers Y, Benes H, Garcia-Borreguero D, Plazzi G, Seboek Kinter D, et al.
CNS Drugs . 2022 Dec; 37(1):93-106. PMID: 36484969
Background And Objective: Daridorexant is a dual orexin receptor antagonist for the treatment of insomnia. In two phase III, 12-week studies in patients with insomnia disorder, daridorexant improved sleep and...
2.
Rosenberg R, Abaluck B, Thein S
J Clin Sleep Med . 2022 Aug; 18(12):2837-2844. PMID: 35975547
Study Objective: Obstructive sleep apnea is a common and serious sleep disorder for which treatment remains challenging due to lack of adherence to approved therapies. Previous pharmacological studies addressing sleep-related...
3.
Coric V, Salloway S, van Dyck C, Dubois B, Andreasen N, Brody M, et al.
JAMA Neurol . 2015 Sep; 72(11):1324-33. PMID: 26414022
Importance: Early identification of Alzheimer disease (AD) is important for clinical management and affords the opportunity to assess potential disease-modifying agents in clinical trials. To our knowledge, this is the...
4.
Coric V, van Dyck C, Salloway S, Andreasen N, Brody M, Richter R, et al.
Arch Neurol . 2012 Aug; 69(11):1430-40. PMID: 22892585
Objective: To assess the safety, tolerability, and pharmacokinetic and pharmacodynamic effects of the -secretase inhibitor avagacestat in patients with mild to moderate Alzheimer disease (AD). Design: Randomized, double-blind, placebo-controlled,24-week phase...