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Stephen T Deyrup

Explore the profile of Stephen T Deyrup including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 152
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Recent Articles
1.
Park Y, Kim E, Deyrup S, Lee J, Shim S
J Nat Prod . 2024 Jul; 87(8):2081-2094. PMID: 39038494
Five new lipopeptaibols (-) and eight new 19-residue peptaibols (-) along with two known lipopeptaibols, lipovelutibols C () and D () were isolated from . The planar structures of the...
2.
Lee S, Park I, Choi J, Son J, Lee J, Hur J, et al.
Org Lett . 2023 Aug; 25(36):6725-6729. PMID: 37650559
Daldipyrenones A-C (-), three unprecedented caged xanthone [6,6,6,6,6] polyketides featuring a spiro-azaphilone unit, were discovered from an endolichenic fungus, 047188. The structures of - were determined by using spectroscopic analysis...
3.
Xie W, Xu X, Xia Y, Shing Lam C, Chen T, Zhi Y, et al.
Bioorg Chem . 2023 Aug; 140:106797. PMID: 37647807
Miliusanes are a class of anticancer lead molecules belonging to meroterpenoids with an 18-carbon skeleton isolated from Miliusa plants. A phytochemical study of the plant M. sinensis was carried out...
4.
Choi J, Lee Y, Kim J, Kwon H, Deyrup S, Lee J, et al.
J Nat Prod . 2023 Apr; 86(4):947-957. PMID: 37042709
In an effort to activate silent biosynthetic gene clusters, DSM42010, a producer of geldanamycin, was cultured at four different pHs (4.5, 5.4, 6.6, and 7.4). An acidic culture condition (pH...
5.
Kim J, Ko H, Hur J, An S, Lee J, Deyrup S, et al.
J Nat Prod . 2022 Dec; 85(12):2804-2816. PMID: 36475432
Adiponectin-synthesis-promoting compounds possess therapeutic potential to treat diverse metabolic diseases, including obesity and diabetes. Phenotypic screening to find adiponectin-synthesis-promoting compounds was performed using the adipogenesis model of human bone marrow...
6.
Lee C, Gong J, Kim J, Ko H, An S, Bang S, et al.
J Nat Prod . 2022 Feb; 85(3):501-510. PMID: 35172097
Three new cyclic peptide-polyketide hybrids (-) and two new chaetiacandin-type polyketides ( and ) along with nine known compounds were isolated from cultures of a halophyte-associated fungus, JS0417. Spectroscopic analysis...
7.
Bang S, Baek J, Kim G, Kim J, Kim S, Deyrup S, et al.
J Nat Prod . 2021 Aug; 84(8):2226-2237. PMID: 34378933
Fourteen azaphilone-type polyketides (-), including nine new ones (- and -), were isolated from cultures of -associated sp. JVF17, and their structures were determined by spectroscopic analysis together with computational...
8.
Xu X, Wang D, Li Y, Deyrup S, Zhang H
Phytochem Rev . 2021 Jun; 21(1):239-289. PMID: 34093097
Medicinal plants are one of the most important sources of antiviral agents and lead compounds. Lignans are a large class of natural compounds comprising two phenyl propane units. Many of...
9.
Deyrup S, Stagnitti N, Perpetua M, Wong-Deyrup S
Biomol Ther (Seoul) . 2021 Feb; 29(2):105-126. PMID: 33632986
Traditional Chinese medicine (TCM) was the primary source of medical treatment for the people inhabiting East Asia for thousands of years. These ancient practices have incorporated a wide variety of...
10.
Wong-Deyrup S, Song X, Ng T, Liu X, Zeng J, Qing Z, et al.
Biomed Pharmacother . 2021 Feb; 137:111348. PMID: 33578237
The ergosterol pathway is a prime antifungal target as it is required for fungal survival, yet is not involved in human homeostasis. Methods to study the ergosterol pathway, however, are...