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Stephen Spellman

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Articles 98
Citations 4304
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Recent Articles
1.
Mehta R, Sparapani R, Wang T, Spellman S, Lee S, Petersdorf E
Am J Hematol . 2025 Mar; PMID: 40056061
No abstract available.
2.
Dong J, Arsang-Jang S, Zhang T, Chen Z, Bolon Y, Spellman S, et al.
J Hematol Oncol . 2025 Feb; 18(1):13. PMID: 39894808
No abstract available.
3.
Dong J, Arsang-Jang S, Zhang T, Chen Z, Bolon Y, Spellman S, et al.
J Hematol Oncol . 2024 Nov; 17(1):104. PMID: 39497145
Mitochondrial DNA (mtDNA) variants in patients with myelodysplastic neoplasms (MDS) are shown to be prognostic of outcomes after allogeneic hematopoietic cell transplantation (allo-HCT). However, the prognostic impact of donor mtDNA...
4.
Guru Murthy G, Zhang T, Bolon Y, Spellman S, Dong J, Auer P, et al.
Biomark Res . 2024 Jan; 12(1):10. PMID: 38273355
Disease relapse remains a major barrier to success after allogeneic hematopoietic cell transplantation (allo-HCT) in myelodysplastic neoplasms (MDS). While certain high risk genomic alterations are associated with increased risk of...
5.
Zhang T, Auer P, Dong J, Cutler C, DeZern A, Gadalla S, et al.
J Hematol Oncol . 2023 Apr; 16(1):37. PMID: 37041565
Recurrent mutations in TP53, RAS pathway and JAK2 genes were shown to be highly prognostic of allogeneic hematopoietic cell transplant (alloHCT) outcomes in myelodysplastic syndromes (MDS). However, a significant proportion...
6.
Narayan R, Niroula A, Wang T, Kuxhausen M, He M, Meyer E, et al.
Transplant Cell Ther . 2023 Mar; 29(7):452.e1-452.e11. PMID: 36997024
Mutation-bearing peptide ligands from mutated nucleophosmin-1 (NPM1) protein have been empirically found to be presented by HLA class I in acute myeloid leukemia (AML). We hypothesized that HLA genotype may...
7.
Dong J, Buradagunta C, Zhang T, Spellman S, Bolon Y, DeZern A, et al.
J Hematol Oncol . 2023 Mar; 16(1):21. PMID: 36899395
Despite mitochondrial DNA (mtDNA) mutations are common events in cancer, their global frequency and clinical impact have not been comprehensively characterized in patients with myelodysplastic neoplasia (also known as myelodysplastic...
8.
Dillon L, Gui G, Page K, Ravindra N, Wong Z, Andrew G, et al.
JAMA . 2023 Mar; 329(9):745-755. PMID: 36881031
Importance: Preventing relapse for adults with acute myeloid leukemia (AML) in first remission is the most common indication for allogeneic hematopoietic cell transplant. The presence of AML measurable residual disease...
9.
Johnstone B, Woods J, Goebel W, Gu D, Lin C, Miller H, et al.
Transplant Cell Ther . 2022 Nov; 29(2):95.e1-95.e10. PMID: 36402456
Despite the readily available graft sources for allogeneic hematopoietic cell transplantation (alloHCT), a significant unmet need remains in the timely provision of suitable unrelated donor grafts. This shortage is related...
10.
Pagliuca S, Gurnari C, Hercus C, Hergalant S, Nadarajah N, Wahida A, et al.
Leukemia . 2022 Oct; 37(1):202-211. PMID: 36253429
Idiopathic aplastic anemia (IAA) pathophysiology is dominated by autoreactivity of human leukocyte antigen (HLA)-restricted T-cells against antigens presented by hematopoietic stem and progenitor cells (HSPCs). Expansion of PIGA and HLA...