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Stephen Sawiak

Explore the profile of Stephen Sawiak including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 339
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Recent Articles
11.
Sampaziotis F, Muraro D, Tysoe O, Sawiak S, Beach T, Godfrey E, et al.
Science . 2021 Feb; 371(6531):839-846. PMID: 33602855
Organoid technology holds great promise for regenerative medicine but has not yet been applied to humans. We address this challenge using cholangiocyte organoids in the context of cholangiopathies, which represent...
12.
Shiba Y, Oikonomidis L, Sawiak S, Fryer T, Hong Y, Cockcroft G, et al.
Biol Psychiatry . 2017 Aug; 82(12):895-903. PMID: 28756869
Background: Impaired regulation of emotional responses to potential threat is a core feature of affective disorders. However, while the subcortical circuitry responsible for processing and expression of fear has been...
13.
Sampaziotis F, Justin A, Tysoe O, Sawiak S, Godfrey E, Upponi S, et al.
Nat Med . 2017 Jul; 23(8):954-963. PMID: 28671689
The treatment of common bile duct (CBD) disorders, such as biliary atresia or ischemic strictures, is restricted by the lack of biliary tissue from healthy donors suitable for surgical reconstruction....
14.
Mikheenko Y, Shiba Y, Sawiak S, Braesicke K, Cockcroft G, Clarke H, et al.
Neuropsychopharmacology . 2015 Jan; 40(6):1395-404. PMID: 25586542
Trait anxiety is a risk factor for the development and maintenance of affective disorders, and insights into the underlying brain mechanisms are vital for improving treatment and prevention strategies. Translational...
15.
Methner C, Buonincontri G, Hu C, Vujic A, Kretschmer A, Sawiak S, et al.
PLoS One . 2014 Jan; 8(12):e83910. PMID: 24391843
Aim: Stimulation of the nitric oxide (NO)--soluble guanylate (sGC)--protein kinase G (PKG) pathway confers protection against acute ischaemia/reperfusion injury, but more chronic effects in reducing post-myocardial infarction (MI) heart failure...