Stephen M Krone
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Explore the profile of Stephen M Krone including associated specialties, affiliations and a list of published articles.
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34
Citations
548
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Recent Articles
1.
Bull J, Krone S
Virus Evol
. 2024 Dec;
10(1):veae100.
PMID: 39717707
Interest in phage therapy-the use of bacterial viruses to treat infections-has increased recently because of the rise of infections with antibiotic-resistant bacteria and the failure to develop new antibiotics to...
2.
Bull J, Wichman H, Krone S, Molineux I
Cells
. 2024 Apr;
13(7.
PMID: 38607024
Recombination among different phages sometimes facilitates their ability to grow on new hosts. Protocols to direct the evolution of phage host range, as might be used in the application of...
3.
Bull J, Wichman H, Krone S
Antibiotics (Basel)
. 2022 Dec;
11(12).
PMID: 36551366
The host ranges of individual phages tend to be narrow, yet many applications of phages would benefit from expanded host ranges. Empirical methods have been developed to direct the evolution...
4.
Karki B, Bull J, Krone S
Virus Evol
. 2022 Jul;
8(2):veac047.
PMID: 35799886
Defective interfering particles (DIPs) are naturally occurring viruses that have evolved to parasitize other viruses. They suppress wild-type (WT) virus infections through their role as intracellular parasites. Because most encode...
5.
Krone S, Tuschhoff B
PeerJ
. 2022 Feb;
10:e12926.
PMID: 35186495
We develop the mathematical structure of the neutral coalescent with both replication-dependent and replication-independent mutations. This allows us to explain and quantify empirical results that explore differences in genetic diversity...
6.
Week B, Nuismer S, Harmon L, Krone S
J Theor Biol
. 2021 Mar;
521:110660.
PMID: 33684405
Although the evolutionary response to random genetic drift is classically modelled as a sampling process for populations with fixed abundance, the abundances of populations in the wild fluctuate over time....
7.
Yuksel M, Remien C, Karki B, Bull J, Krone S
Evol Med Public Health
. 2021 Mar;
9(1):1-10.
PMID: 33664955
Background And Objectives: Genetic engineering and similar technologies offer promising new approaches to controlling human diseases by blocking transmission from vectors. However, in spatially structured populations, imperfect coverage of the...
8.
Tyson R, Hamilton S, Lo A, Baumgaertner B, Krone S
Bull Math Biol
. 2020 Jan;
82(1):14.
PMID: 31932981
During an epidemic, the interplay of disease and opinion dynamics can lead to outcomes that are different from those predicted based on disease dynamics alone. Opinions and the behaviours they...
9.
Bull J, Remien C, Gomulkiewicz R, Krone S
PeerJ
. 2019 Nov;
7:e7921.
PMID: 31681512
Gene drives may be used in two ways to curtail vectored diseases. Both involve engineering the drive to spread in the vector population. One approach uses the drive to directly...
10.
Bull J, Remien C, Krone S
Evol Med Public Health
. 2019 Jun;
2019(1):66-81.
PMID: 31191905
Background And Objectives: Genetic engineering combined with CRISPR technology has developed to the point that gene drives can, in theory, be engineered to cause extinction in countless species. Success of...