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Stephen L Shiao

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Articles 68
Citations 2873
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Recent Articles
1.
Shiao S, Gouin 3rd K, Ing N, Ho A, Basho R, Shah A, et al.
Cancer Cell . 2024 Jan; 42(1):70-84.e8. PMID: 38194915
Strategies are needed to better identify patients that will benefit from immunotherapy alone or who may require additional therapies like chemotherapy or radiotherapy to overcome resistance. Here we employ single-cell...
2.
Monjazeb A, Daly M, Luxardi G, Maverakis E, Merleev A, Marusina A, et al.
Nat Commun . 2023 Sep; 14(1):5332. PMID: 37658083
Stereotactic ablative radiotherapy (SABR) is a standard-of-care for medically-inoperable-early-stage non-small cell lung cancer (NSCLC). One third of patients progress and chemotherapy is rarely used in this population. We questioned if...
3.
Kirkness J, Dusting J, Eikelis N, Pirakalathanan P, DeMarco J, Shiao S, et al.
Front Med Technol . 2023 Jul; 5:1148310. PMID: 37440838
Introduction: X-ray Velocimetry (XV) ventilation analysis is a 4-dimensional imaging-based method for quantifying regional ventilation, aiding in the assessment of lung function. We examined the performance characteristics of XV ventilation...
4.
Gavil N, Scott M, Weyu E, Smith O, OFlanagan S, Wijeyesinghe S, et al.
Sci Immunol . 2023 Jun; 8(84):eadd5976. PMID: 37267383
Analyses of healthy tissue reveal signatures that identify resident memory CD8 T cells (T), which survey tissues without recirculating. The density of T phenotype cells within solid tumors correlates favorably...
5.
Ryu S, Deshmukh S, Timmerman R, Movsas B, Gerszten P, Yin F, et al.
JAMA Oncol . 2023 Apr; 9(6):800-807. PMID: 37079324
Importance: Spine metastasis can be treated with high-dose radiation therapy with advanced delivery technology for long-term tumor and pain control. Objective: To assess whether patient-reported pain relief was improved with...
6.
Chung E, Nguyen A, Mirhadi A, Steers J, Phillips T, Atkins K, et al.
Brachytherapy . 2023 Mar; 22(3):361-367. PMID: 36997449
Purpose: Accelerated partial breast irradiation (APBI) delivered with high-dose-rate brachytherapy is a standard of care treatment typically delivered over 10 fractions. The TRIUMPH-T multi-institutional study recently demonstrated promising results using...
7.
Miyaguchi K, Wang H, Black K, Shiao S, Wang R, Yu J
Sci Rep . 2023 Jan; 13(1):196. PMID: 36604465
Naïve T cells become effector T cells following stimulation by antigen-loaded dendritic cells (DCs) and sequential cytokine activation. We aimed to develop procedures to efficiently activate T cells with tumor-associated...
8.
Shibata T, Cao D, Dar T, Ahmed F, Bhat S, Veiras L, et al.
Cancers (Basel) . 2022 Nov; 14(21). PMID: 36358691
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive disease with poor prognosis, which is mainly due to drug resistance. The biology determining the response to chemo-radiotherapy in...
9.
Tessaro F, Ko E, De Simone M, Piras R, Broz M, Goodridge H, et al.
Cell Rep . 2022 Jun; 39(12):110977. PMID: 35732118
The standard of care is unsuccessful to treat recurrent and aggressive soft-tissue sarcomas. Interventions aimed at targeting components of the tumor microenvironment have shown promise for many solid tumors yet...
10.
Nguyen A, Luu M, Nguyen V, Lu D, Shiao S, Kamrava M, et al.
J Natl Cancer Inst . 2022 Mar; 114(7):1003-1011. PMID: 35311991
Background: Nodal staging systems vary substantially across solid tumors, implying heterogeneity in the behavior of nodal variables in various contexts. We hypothesized, in contradiction to this, that metastatic lymph node...