Stephen Kadlecek
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Explore the profile of Stephen Kadlecek including associated specialties, affiliations and a list of published articles.
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61
Citations
547
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Recent Articles
1.
Ruppert K, Loza L, Hamedani H, Ismail M, Chen J, Duncan I, et al.
Magn Reson Med
. 2024 Nov;
93(3):902-915.
PMID: 39503293
Purpose: To compare pulmonary function metrics obtained with hyperpolarized xenon-129 (HXe) MRS, using chemical shift saturation recovery (CSSR) and CSI-CSSR, in healthy rats and a rat model of radiation-induced lung...
2.
Ruppert K, Loza L, Amzajerdian F, Hamedani H, Baron R, Kadlecek S, et al.
J Vis Exp
. 2023 Nov;
(201).
PMID: 38009715
Hyperpolarized Xenon-129 (HXe) magnetic resonance imaging (MRI) provides tools for obtaining 2- or 3-dimensional maps of lung ventilation patterns, gas diffusion, Xenon uptake by lung parenchyma, and other lung function...
3.
Amzajerdian F, Hamedani H, Baron R, Loza L, Duncan I, Ruppert K, et al.
Magn Reson Med
. 2023 Aug;
90(6):2334-2347.
PMID: 37533368
Purpose: To demonstrate the feasibility of a multi-breath xenon-polarization transfer contrast (XTC) MR imaging approach for simultaneously evaluating regional ventilation and gas exchange parameters. Methods: Imaging was performed in five...
4.
Kadlecek S, Friedlander Y, Virgincar R
Molecules
. 2022 Dec;
27(23).
PMID: 36500430
Although critical for development of novel therapies, understanding altered lung function in disease models is challenging because the transport and diffusion of gases over short distances, on which proper function...
5.
Xin Y, Cereda M, Yehya N, Humayun S, Delvecchio P, Thompson J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2022 Apr;
322(6):L866-L872.
PMID: 35438574
Imatinib, a tyrosine kinase inhibitor, attenuates pulmonary edema and inflammation in lung injury. However, the physiological effects of this drug and their impact on outcomes are poorly characterized. Using serial...
6.
Hamedani H, Ma K, DiBardino D, Baron R, Kadlecek S, Amzajerdian F, et al.
Am J Respir Crit Care Med
. 2022 Jan;
205(9):e48-e50.
PMID: 35044897
No abstract available.
7.
Friedlander Y, Zanette B, Lindenmaier A, Li D, Kadlecek S, Santyr G, et al.
Magn Reson Med
. 2021 Nov;
87(4):1971-1979.
PMID: 34841605
Purpose: To demonstrate the feasibility of Xe chemical shift saturation recovery (CSSR) combined with spiral-IDEAL imaging for simultaneous measurement of the time-course of red blood cell (RBC) and brain tissue...
8.
Baron R, Kadlecek S, Loza L, Xin Y, Amzajerdian F, Duncan I, et al.
Acad Radiol
. 2021 Jul;
29 Suppl 2:S127-S136.
PMID: 34272162
Purpose: This study aims to develop and validate a parametric response mapping (PRM) methodology to accurately identify diseased regions of the lung by using variable thresholds to account for alterations...
9.
Hamedani H, Kadlecek S, Ruppert K, Xin Y, Duncan I, Rizi R
J Physiol
. 2021 Jul;
599(17):4197-4223.
PMID: 34256417
Key Points: Multibreath imaging to estimate regional gas mixing efficiency is superior to intensity-based single-breath ventilation markers, as it is capable of revealing minute but essential measures of ventilation heterogeneity...
10.
Xin Y, Martin K, Morais C, Delvecchio P, Gerard S, Hamedani H, et al.
Crit Care Med
. 2021 May;
49(10):e1015-e1024.
PMID: 33938714
Objectives: It is not known how lung injury progression during mechanical ventilation modifies pulmonary responses to prone positioning. We compared the effects of prone positioning on regional lung aeration in...