Stephen J Paisey
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Explore the profile of Stephen J Paisey including associated specialties, affiliations and a list of published articles.
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15
Citations
151
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Recent Articles
1.
Sap J, Meyer C, Ford J, Straathof N, Durr A, Lelos M, et al.
Nature
. 2022 Mar;
606(7912):102-108.
PMID: 35344982
The advent of total-body positron emission tomography (PET) has vastly broadened the range of research and clinical applications of this powerful molecular imaging technology. Such possibilities have accelerated progress in...
2.
Exner R, Paisey S, Redman J, Pascu S
ACS Omega
. 2021 Nov;
6(43):28455-28462.
PMID: 34746541
Peptide nucleic acids (PNAs, nucleic acid analogues with a peptide backbone rather than a phosphoribosyl backbone) have emerged as promising chemical agents in antigene or antisense therapeutics, as splicing modulators...
3.
Fenwick A, Collins S, Evans W, Ferreira K, Paisey S, Robinson A, et al.
Appl Radiat Isot
. 2020 Sep;
166:109294.
PMID: 32977243
An absolute standardisation of Zr was performed alongside determination of gamma emission intensities and half-life. The collected data were evaluated alongside complementary works from previous publications and new recommended nuclear...
4.
Kiraga L, Cerutti G, Braniewska A, Strzemecki D, Sas Z, Boffi A, et al.
Int J Mol Sci
. 2020 Jul;
21(14).
PMID: 32679799
Proteins, as a major component of organisms, are considered the preferred biomaterials for drug delivery vehicles. Hemoglobin (Hb) has been recently rediscovered as a potential drug carrier, but its use...
5.
Dang Z, Avolio E, Thomas A, Faulkner A, Beltrami A, Cervellin C, et al.
Eur J Heart Fail
. 2020 May;
22(9):1568-1581.
PMID: 32384208
Aims: Homozygosity for a four-missense single-nucleotide polymorphism haplotype of the human BPIFB4 gene is enriched in long-living individuals. Delivery of this longevity-associated variant (LAV) improved revascularisation and reduced endothelial dysfunction...
6.
Cavaliere A, Probst K, Paisey S, Marshall C, Dheere A, Aigbirhio F, et al.
Molecules
. 2020 Feb;
25(3).
PMID: 32041321
Phosphoramidate pro-nucleotides (ProTides) have revolutionized the field of anti-viral and anti-cancer nucleoside therapy, overcoming the major limitations of nucleoside therapies and achieving clinical and commercial success. Despite the translation of...
7.
Watson H, Durairaj R, Ohme J, Alatsatianos M, Almutairi H, Mohammed R, et al.
Front Immunol
. 2019 Jun;
10:1321.
PMID: 31249570
The homing molecule, L-selectin (CD62L), is commonly used as a T cell activation marker, since expression is downregulated following engagement of the T cell receptor. Studies in mice have shown...
8.
Trueman R, Diaz C, Farr T, Harrison D, Fuller A, Tokarczuk P, et al.
J Cereb Blood Flow Metab
. 2016 Jun;
37(4):1349-1361.
PMID: 27317655
In order to test therapeutics, functional assessments are required. In pre-clinical stroke research, there is little consensus regarding the most appropriate behavioural tasks to assess deficits, especially when testing over...
9.
Knight J, Paisey S, Dabkowski A, Marculescu C, Williams A, Marshall C, et al.
Dalton Trans
. 2016 Mar;
45(15):6343-7.
PMID: 26986633
The most widely cited procedures for radiolabeling antibodies with zirconium-89 for immuno-PET require multi-milligram amounts of antibody which can be cost-prohibitive, particularly during the research and development process. We therefore...
10.
Knight J, Hallett A, Brancale A, Paisey S, Clarkson R, Edwards P
Chembiochem
. 2011 Oct;
12(17):2692-8.
PMID: 21998043
AMD3100 is a potent and selective antagonist of the CXCR4 receptor; it has been shown to block the route of entry of HIV into host T-cells. This compound and its...