Stephen J Fedak
Overview
Explore the profile of Stephen J Fedak including associated specialties, affiliations and a list of published articles.
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Articles
2
Citations
162
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0
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Recent Articles
1.
Linsalata A, He F, Malik A, Glineburg M, Green K, Natla S, et al.
EMBO Rep
. 2019 Jul;
20(9):e47498.
PMID: 31347257
A CGG trinucleotide repeat expansion in the 5' UTR of FMR1 causes the neurodegenerative disorder Fragile X-associated tremor/ataxia syndrome (FXTAS). This repeat supports a non-canonical mode of protein synthesis known...
2.
Green K, Glineburg M, Kearse M, Flores B, Linsalata A, Fedak S, et al.
Nat Commun
. 2017 Dec;
8(1):2005.
PMID: 29222490
Repeat-associated non-AUG (RAN) translation allows for unconventional initiation at disease-causing repeat expansions. As RAN translation contributes to pathogenesis in multiple neurodegenerative disorders, determining its mechanistic underpinnings may inform therapeutic development....