Stephen J Elvin
Overview
Explore the profile of Stephen J Elvin including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
243
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Recent Articles
1.
Reithmeier-Rost D, Hill J, Elvin S, Williamson D, Dittmann S, Schmid A, et al.
Microbes Infect
. 2007 Jun;
9(8):997-1002.
PMID: 17556003
Yersinia pestis and the enteropathogenic Yersinia pseudotuberculosis and Yersinia enterocolitica share the virulence-antigen LcrV. Previously, using reverse genetics we have proven that LcrV contributes to the virulence of Y. enterocolitica...
2.
Tanabe M, Atkins H, Harland D, Elvin S, Stagg A, Mirza O, et al.
Infect Immun
. 2006 May;
74(6):3687-91.
PMID: 16714605
The identification of Yersinia pestis as a potential bioterrorism agent and the emergence of antibiotic-resistant strains have highlighted the need for improved vaccines and treatments for plague. The aim of...
3.
Hill J, Eyles J, Elvin S, Healey G, Lukaszewski R, Titball R
Infect Immun
. 2006 Apr;
74(5):3068-70.
PMID: 16622253
Intratracheal delivery of aerosolized monoclonal antibodies with specificity for Yersinia pestis LcrV and F1 antigens protected mice in a model of pneumonic plague. These data support the utility of inhaled...
4.
Elvin S, Eyles J, Howard K, Ravichandran E, Somavarappu S, Alpar H, et al.
Vaccine
. 2006 Mar;
24(20):4433-9.
PMID: 16546306
Protection against virulent plague challenge by the parenteral and aerosol routes was afforded by a single administration of microencapsulated Caf1 and LcrV antigens from Yersinia pestis in BALB/c mice. Recombinant...
5.
Elvin S, Healey G, Westwood A, Knight S, Eyles J, Williamson E
Infect Immun
. 2006 Feb;
74(3):1706-11.
PMID: 16495542
Burkholderia pseudomallei, the causative agent of melioidosis, is a gram-negative bacterium which can cause either chronic infections or acute lethal sepsis in infected individuals. The disease is endemic in Southeast...
6.
Westwood A, Elvin S, Healey G, Williamson E, Eyles J
Vaccine
. 2005 Nov;
24(11):1736-43.
PMID: 16278038
Certain toll-like receptor (TLR) agonists, e.g. CpG DNA, can be used as potent vaccine 'adjuvants'. It is known that some sequences of single stranded (ss) RNA stimulate proinflammatory and antiviral...
7.
Healey G, Elvin S, Morton M, Williamson E
Infect Immun
. 2005 Aug;
73(9):5945-51.
PMID: 16113315
Burkholderia pseudomallei, the causative agent of melioidosis, is a gram-negative bacillus endemic to areas of southeast Asia and northern Australia. Presently, there is no licensed vaccine for B. pseudomallei and...
8.
Garmory H, Leckenby M, Griffin K, Elvin S, Taylor R, Hartley M, et al.
Infect Immun
. 2005 Mar;
73(4):2005-11.
PMID: 15784541
Live, attenuated bacteria are effective vectors for heterologous antigen delivery. However, loss of heterologous gene-bearing plasmids is problematic, and antibiotics and their resistance genes are not desirable for in vivo...
9.
Elvin S, Williamson E
Microb Pathog
. 2004 Oct;
37(4):177-84.
PMID: 15458778
The Caf1 and LcrV sub-unit vaccine for plague has been shown to be highly protective against challenge with virulent Yersinia pestis in a mouse model. Production of large amounts of...
10.
Elvin S, Williamson E, Scott J, Smith J, Perez De Lema G, Chilla S, et al.
Nature
. 2004 Jul;
430(6998):417.
PMID: 15272490
Mecsas and colleagues suggest that a deficiency in the chemokine receptor CCR5 in humans is unlikely to confer protection against plague, based on their study of Yersinia pestis infection in...