Stephen C Lazarus
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Explore the profile of Stephen C Lazarus including associated specialties, affiliations and a list of published articles.
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4683
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Recent Articles
11.
Burkes R, Couper D, Barjaktarevic I, Cooper C, Labaki W, Han M, et al.
Chronic Obstr Pulm Dis
. 2021 Apr;
8(2):277-291.
PMID: 33829714
Introduction: Age and vitamin D levels may affect symptom burden in chronic obstructive pulmonary disease (COPD). We used the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) to determine...
12.
Clougherty J, Kinnee E, Cardet J, Mauger D, Bacharier L, Beigelman A, et al.
Lancet Respir Med
. 2021 Feb;
9(4):330-332.
PMID: 33539731
No abstract available.
13.
Dunican E, Elicker B, Henry T, Gierada D, Schiebler M, Anderson W, et al.
Am J Respir Crit Care Med
. 2020 Nov;
203(8):957-968.
PMID: 33180550
The relative roles of mucus plugs and emphysema in mechanisms of airflow limitation and hypoxemia in smokers with chronic obstructive pulmonary disease (COPD) are uncertain. To relate image-based measures of...
14.
Novel Respiratory Disability Score Predicts COPD Exacerbations and Mortality in the SPIROMICS Cohort
Cooper C, Paine R, Curtis J, Kanner R, Martinez C, Meldrum C, et al.
Int J Chron Obstruct Pulmon Dis
. 2020 Aug;
15:1887-1898.
PMID: 32821092
Rationale: Some COPD patients develop extreme breathlessness, decreased exercise capacity and poor health status yet respiratory disability is poorly characterized as a distinct phenotype. Objective: To define respiratory disability in...
15.
Leitao Filho F, Mattman A, Schellenberg R, Criner G, Woodruff P, Lazarus S, et al.
Chest
. 2020 May;
158(4):1420-1430.
PMID: 32439504
Background: Hypogammaglobulinemia (serum IgG levels < 7.0 g/L) has been associated with increased risk of COPD exacerbations but has not yet been shown to predict hospitalizations. Research Question: To determine...
16.
Woodruff P, Lazarus S
JAMA Intern Med
. 2020 Mar;
180(5):686-687.
PMID: 32119027
No abstract available.
17.
Dransfield M, Voelker H, Bhatt S, Brenner K, Casaburi R, Come C, et al.
N Engl J Med
. 2019 Oct;
381(24):2304-2314.
PMID: 31633896
Background: Observational studies suggest that beta-blockers may reduce the risk of exacerbations and death in patients with moderate or severe chronic obstructive pulmonary disease (COPD), but these findings have not...
18.
Wechsler M, Szefler S, Ortega V, Pongracic J, Chinchilli V, Lima J, et al.
N Engl J Med
. 2019 Sep;
381(13):1227-1239.
PMID: 31553835
Background: Morbidity from asthma is disproportionately higher among black patients than among white patients, and black patients constitute the minority of participants in trials informing treatment. Data indicate that patients...
19.
Grossman N, Ortega V, King T, Bleecker E, Ampleford E, Bacharier L, et al.
J Allergy Clin Immunol
. 2019 Sep;
144(6):1524-1533.
PMID: 31520679
Background: Minority groups of African descent experience disproportionately greater asthma morbidity compared with other racial groups, suggesting that genetic variation from a common ancestry could influence exacerbation risk. Objective: We...
20.
Lazarus S, Krishnan J, King T, Lang J, Blake K, Covar R, et al.
N Engl J Med
. 2019 May;
380(21):2009-2019.
PMID: 31112384
Background: In many patients with mild, persistent asthma, the percentage of eosinophils in sputum is less than 2% (low eosinophil level). The appropriate treatment for these patients is unknown. Methods:...