Stephen C Frederico
Overview
Explore the profile of Stephen C Frederico including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
101
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0
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Recent Articles
1.
Almeida T, Reyes J, Scanlon S, Frederico S, Huq S, Hadjipanayis C
Expert Rev Neurother
. 2025 Feb;
:1-11.
PMID: 39991830
Introduction: Laser Interstitial Thermal Therapy (LITT) has emerged as a promising minimally invasive treatment option for recurrent brain metastases, especially for patients who have previously undergone Stereotactic Radiosurgery (SRS). Despite...
2.
Nader N, Frederico S, Miller T, Huq S, Zhang X, Kohanbash G, et al.
Cancers (Basel)
. 2024 Oct;
16(19).
PMID: 39409893
Glioblastoma (GBM) is an aggressive primary brain tumor depicted by a cold tumor microenvironment, low immunogenicity, and limited effective therapeutic interventions. Its location in the brain, a highly immune-selective organ,...
3.
Nisnboym M, Sneiderman C, Jaswal A, Xiong Z, Vincze S, Sever R, et al.
Expert Rev Clin Immunol
. 2024 Oct;
21(2):239-247.
PMID: 39402706
Background: Glioblastoma (GBM) is an aggressive cancer with limited treatment options. Immunotherapy targeting CD69, an early activation marker on T cells, has shown promise in preclinical models of non-CNS malignancies....
4.
Raphael I, Mujeeb A, Ampudia-Mesias E, Sever R, McClellan B, Frederico S, et al.
bioRxiv
. 2024 Sep;
PMID: 39314283
Statement Of Significance: We demonstrate mechanisms of the druggable glioma-derived CD200 checkpoint on tumor growth and immune suppression.
5.
Frederico S, Raphael I, Nisnboym M, Huq S, Schlegel B, Sneiderman C, et al.
Expert Rev Clin Immunol
. 2024 Aug;
20(11):1411-1420.
PMID: 39114885
Objectives: Despite surgical resection, chemoradiation, and targeted therapy, brain tumors remain a leading cause of cancer-related death in children. Immunotherapy has shown some promise and is actively being investigated for...
6.
Pollack I, Felker J, Frederico S, Raphael I, Kohanbash G
Childs Nerv Syst
. 2024 Jun;
40(10):3263-3275.
PMID: 38884777
Pediatric low-grade gliomas (pLGGs) are the most common brain tumor types affecting children. Although gross-total resection remains the treatment of choice, many tumors are not amenable to complete removal, because...
7.
Frederico S, Sharma N, Darling C, Taori S, Dubinsky A, Zhang X, et al.
Front Pediatr
. 2024 Mar;
12:1346493.
PMID: 38523840
Pediatric high-grade glioma (pHGG) including pediatric glioblastoma (pGBM) are highly aggressive pediatric central nervous system (CNS) malignancies. pGBM comprises approximately 3% of all pediatric CNS malignancies and has a 5-year...
8.
Vincze S, Jaswal A, Frederico S, Nisnboym M, Li B, Xiong Z, et al.
Sci Rep
. 2024 Mar;
14(1):5305.
PMID: 38438420
Glioblastoma (GBM) is the most common primary malignant brain tumor. Currently, there are few effective treatment options for GBM beyond surgery and chemo-radiation, and even with these interventions, median patient...
9.
Neoadjuvant immune checkpoint inhibition in the management of glioblastoma: Exploring a new frontier
Frederico S, Darling C, Bielanin J, Dubinsky A, Zhang X, Hadjipanayis C, et al.
Front Immunol
. 2023 Mar;
14:1057567.
PMID: 36875096
Brain tumors are one of the leading causes of cancer related death in both the adult and pediatric patient population. Gliomas represent a cohort of brain tumors derived from glial...
10.
Frederico S, Vera E, Abdullaev Z, Acquaye A, Aldape K, Boris L, et al.
Front Oncol
. 2023 Feb;
13:1099618.
PMID: 36741001
The uncommon -altered primary central nervous system (CNS) tumors were recently added to the World Health Organization 2021 classification under the name Astroblastoma, -altered. Another term used to describe them,...