Stephen C Benz
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Explore the profile of Stephen C Benz including associated specialties, affiliations and a list of published articles.
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23
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1466
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Recent Articles
1.
Cook C, Taylor M, Liu Y, Schmidt R, Sedgewick A, Kim E, et al.
Cell Rep Med
. 2022 Aug;
3(8):100715.
PMID: 35977472
The homeostatic mechanisms that fail to restrain chronic tissue inflammation in diseases, such as psoriasis vulgaris, remain incompletely understood. We profiled transcriptomes and epitopes of single psoriatic and normal skin-resident...
2.
Reimann H, Nguyen A, Sanborn J, Vaske C, Benz S, Niazi K, et al.
J Immunother Cancer
. 2021 Jun;
9(6).
PMID: 34172517
Background: Therapeutic regimens designed to augment the immunological response of a patient with breast cancer (BC) to tumor tissue are critically informed by tumor mutational burden and the antigenicity of...
3.
Liu Y, Cook C, Sedgewick A, Zhang S, Fassett M, Ricardo-Gonzalez R, et al.
iScience
. 2020 Nov;
23(10):101582.
PMID: 33205009
Inflammatory response heterogeneity has impeded high-resolution dissection of diverse immune cell populations during activation. We characterize mouse cutaneous immune cells by single-cell RNA sequencing, after inducing inflammation using imiquimod and...
4.
Kang T, Yau C, Wong C, Sanborn J, Newton Y, Vaske C, et al.
Breast Cancer Res
. 2020 Aug;
22(1):81.
PMID: 32736587
Background: Previous studies have identified and validated a risk-associated Active transcriptome phenotype commonly expressed in the cancer-adjacent and histologically normal epithelium, stroma, and adipose containing peritumor microenvironment of clinically established...
5.
Adashek J, Kato S, Parulkar R, Szeto C, Sanborn J, Vaske C, et al.
JCI Insight
. 2020 Jun;
5(11).
PMID: 32493840
Next-generation sequencing (NGS) has not revealed all the mechanisms underlying resistance to genomically matched drugs. Here, we performed in 1417 tumors whole-exome tumor (somatic)/normal (germline) NGS and whole-transcriptome sequencing, the...
6.
Solocinski K, Padget M, Fabian K, Wolfson B, Cecchi F, Hembrough T, et al.
J Immunother Cancer
. 2020 Apr;
8(1).
PMID: 32345623
Background: Natural killer (NK) cells are immune cells capable of killing virally infected cells and tumor cells without the need for antigen stimulation. Tumors, however, can create a suppressive microenvironment...
7.
Jaber M, Song B, Taylor C, Vaske C, Benz S, Rabizadeh S, et al.
Breast Cancer Res
. 2020 Jan;
22(1):12.
PMID: 31992350
Background: Breast cancer intrinsic molecular subtype (IMS) as classified by the expression-based PAM50 assay is considered a strong prognostic feature, even when controlled for by standard clinicopathological features such as...
8.
Heskett M, Sanborn J, Boniface C, Goode B, Chapman J, Garg K, et al.
Mod Pathol
. 2020 Jan;
33(6):1193-1206.
PMID: 31911616
Immature teratoma is a subtype of malignant germ cell tumor of the ovary that occurs most commonly in the first three decades of life, frequently with bilateral ovarian disease. Despite...
9.
Lee K, Benz S, Hicks K, Nguyen A, Gameiro S, Palena C, et al.
Cancer Immunol Res
. 2019 Jul;
7(8):1359-1370.
PMID: 31292145
Progressive tumor growth is associated with deficits in the immunity generated against tumor antigens. Vaccines targeting tumor neoepitopes have the potential to address qualitative defects; however, additional mechanisms of immune...
10.
North J, Solomon D, Golovato J, Bloomer M, Benz S, Cho R
J Cutan Pathol
. 2019 Jun;
46(10):736-741.
PMID: 31148199
Background: Sebaceous carcinoma (SeC) is an uncommon malignancy arising from sebaceous glands of the conjunctiva and skin. Recurrent mutations in the ZNF750 were recently identified in ocular SeC. We assessed...