Stephen Brooks
Overview
Explore the profile of Stephen Brooks including associated specialties, affiliations and a list of published articles.
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Articles
51
Citations
897
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Recent Articles
1.
Chen K, De Giovanni M, Xu Y, An J, Kirthivasan N, Lu E, et al.
Cell
. 2024 Dec;
188(4):1019-1035.e22.
PMID: 39708807
Sustained lymphocyte migration from blood into lymph nodes (LNs) is important for immune responses. The CC-chemokine receptor-7 (CCR7) ligand CCL21 is required for LN entry but is downregulated during inflammation,...
2.
Nakabo S, Sandoval-Heglund D, Hanata N, Brooks S, Hoffmann V, Zhang M, et al.
Front Immunol
. 2024 Dec;
15:1465185.
PMID: 39664388
Objectives: An important pathogenic role for neutrophils in systemic lupus erythematosus (SLE) has been proposed. Neutrophils that lack brain and muscle aryl hydrocarbon receptor nuclear translocator-like 1 (), one of...
3.
Hopperton K, ONeill E, Chakrabarti S, Stanton M, Parnel S, Arbuckle T, et al.
Am J Clin Nutr
. 2024 Oct;
120(6):1419-1431.
PMID: 39362363
Background: Human milk (HM) composition data are widely used in clinical, regulatory, and public health initiatives. The existing HM profiles in United States and Canadian nutrient databanks are outdated and...
4.
Oliveira C, Temesgen-Oyelakin Y, Naqi M, Davis M, Naz F, DellOrso S, et al.
Arthritis Rheumatol
. 2024 Jun;
76(10):1501-1511.
PMID: 38923259
Objective: Systemic lupus erythematosus (SLE) increases cardiovascular disease (CVD) risk, and this is not explained by traditional risk factors. Characterization of blood immunologic signatures that associate with subclinical CVD and...
5.
Patino-Martinez E, Nakabo S, Jiang K, Carmona-Rivera C, Tsai W, Claybaugh D, et al.
medRxiv
. 2024 Apr;
PMID: 38605883
Objective: The Krebs cycle enzyme Aconitate Decarboxylase 1 (ACOD1) mediates itaconate synthesis in myeloid cells.. Previously, we reported that administration of 4-octyl itaconate abrogated lupus phenotype in mice. Here, we...
6.
Fernando N, Gopalakrishnan J, Behensky A, Reich L, Liu C, Bass V, et al.
bioRxiv
. 2023 Apr;
PMID: 37090642
Alzheimer's disease (AD) is the leading cause of dementia worldwide, but there are limited therapeutic options and no current cure. While the involvement of microglia in AD has been highly...
7.
Wigerblad G, Warner S, Ramos-Benitez M, Kardava L, Tian X, Miao R, et al.
Sci Adv
. 2023 Jan;
9(1):eade8272.
PMID: 36598976
Spleen tyrosine kinase (SYK) is a previously unidentified therapeutic target that inhibits neutrophil and macrophage activation in coronavirus disease 2019 (COVID-19). Fostamatinib, a SYK inhibitor, was studied in a phase...
8.
Wigerblad G, Cao Q, Brooks S, Naz F, Gadkari M, Jiang K, et al.
J Immunol
. 2022 Jul;
209(4):772-782.
PMID: 35858733
Neutrophils are the most abundant leukocytes in human blood and are essential components of innate immunity. Until recently, neutrophils were considered homogeneous and transcriptionally inactive cells, but both concepts are...
9.
Tajiri H, Suzuki M, Bessho K, Ito Y, Murakami J, Hatori R, et al.
Sci Rep
. 2022 Jul;
12(1):11205.
PMID: 35778417
At present, noninvasive fibrosis markers are not available for the assessment of liver fibrosis in children with chronic hepatitis C. Sixty-three children with chronic hepatitis C were included. Changes in...
10.
Oldekop J, Rasmussen L, Agrawal A, Bebbington A, Meyfroidt P, Bengston D, et al.
Nat Plants
. 2020 Dec;
6(12):1400-1407.
PMID: 33257859
Forests have re-taken centre stage in global conversations about sustainability, climate and biodiversity. Here, we use a horizon scanning approach to identify five large-scale trends that are likely to have...