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Stephen Bourke

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Citations 609
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Recent Articles
1.
Gramegna A, Aliberti S, Amorim A, Blasi F, Bourke S, Burgel P, et al.
J Cyst Fibros . 2023 Nov; 23(2):306-313. PMID: 37949745
Background: Although cystic fibrosis (CF) standards of care have been produced and regularly updated, they are not specifically targeting at the adult population. The ECFS Standards of Care Project established...
2.
Mossop M, Robinson L, Jiang J, Peleg A, Blakeway L, Macesic N, et al.
J Med Microbiol . 2023 Jun; 72(6). PMID: 37289488
One third of people with CF in the UK are co-infected by both and . Chronic bacterial infection in CF contributes to the gradual destruction of lung tissue, and eventually...
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Al-Momani H, Perry A, Nelson A, Stewart C, Jones R, Krishnan A, et al.
Sci Rep . 2022 Jun; 12(1):11114. PMID: 35773410
Studies of microbiota reveal inter-relationships between the microbiomes of the gut and lungs. This relationship may influence the progression of lung disease, particularly in patients with cystic fibrosis (CF), who...
5.
Hesse K, Bourke S, Steer J
Respir Med . 2022 Mar; 196:106800. PMID: 35306385
Background: Patients surviving hospitalization for exacerbations of chronic obstructive pulmonary disease (ECOPD) are at heightened risk of cardiovascular events. Heart failure is often underdiagnosed and undertreated in COPD; better care...
6.
Lawless M, Burgess M, Bourke S
Medicina (Kaunas) . 2022 Jan; 58(1). PMID: 35056374
Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide. Acute exacerbations (AECOPD) are common and often triggered by viral infection. During the COVID-19 pandemic social restrictions, including...
7.
Bevan A, Hoo Z, Totton N, Girling C, Davids I, Whelan P, et al.
J Cyst Fibros . 2021 Sep; 21(2):323-331. PMID: 34565705
Background: Studies in separate cohorts suggest possible discrepancies between inhaled medicines supplied (median 50-60%) and medicines used (median 30-40%). We performed the first study that directly compares CF medicine supply...
8.
Haq I, Althaus M, Gardner A, Yeoh H, Joshi U, Saint-Criq V, et al.
Am J Physiol Lung Cell Mol Physiol . 2020 Dec; 320(2):L288-L300. PMID: 33296276
Cystic fibrosis (CF) arises from mutations in the CF transmembrane conductance regulator () gene, resulting in progressive and life-limiting respiratory disease. R751L is a rare CFTR mutation that is poorly...
9.
Echevarria C, Steer J, Wason J, Bourke S
Emerg Med J . 2020 Nov; 38(3):170-177. PMID: 33243839
Background: In hospitalised patients with exacerbation of Chronic Obstructive Pulmonary Disease, European and British guidelines endorse oxygen target saturations of 88%-92%, with adjustment to 94%-98% if carbon dioxide levels are...
10.
Miller M, Lee R, Yates S, Billett H, Bourke S, Flight W, et al.
BMJ Support Palliat Care . 2020 Aug; 12(3):296-298. PMID: 32839209
Background: Cystic Fibrosis (CF) is a life-limiting illness. Audit of the care of patients dying of CF has not been published to date. Methods: Newcastle and Oxford teams adapted the...