Stephen B Wheatcroft
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Explore the profile of Stephen B Wheatcroft including associated specialties, affiliations and a list of published articles.
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99
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2229
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Recent Articles
1.
Luk C, Bridge K, Warmke N, Simmons K, Drozd M, Moran A, et al.
Nat Commun
. 2025 Jan;
16(1):170.
PMID: 39747815
During recent decades, changes in lifestyle have led to widespread nutritional obesity and its related complications. Remodelling adipose tissue as a therapeutic goal for obesity and its complications has attracted...
2.
Myers C, Viswambharan H, Haywood N, Bridge K, Turvey S, Armstrong T, et al.
Mol Cell Endocrinol
. 2024 Oct;
594():112387.
PMID: 39419341
Objectives: The insulin receptor (IR) and insulin like growth factor-1 receptor (IGF-1R) are heterodimers consisting of two extracellular α-subunits and two transmembrane β -subunits. Insulin αβ and insulin like growth...
3.
Maqbool A, Viswambharan H, Skromna A, Makava N, Shawer H, Bridge K, et al.
Vasc Biol
. 2024 Oct;
6(1).
PMID: 39401163
Insulin resistance underpins the progression of type 2 diabetes mellitus and leads to a collection of risk factors for the development of atherosclerosis. Whether or not insulin resistance at a...
4.
Wood N, Critchlow A, Cheng C, Straw S, Hendrickse P, Pereira M, et al.
Circ Heart Fail
. 2024 Oct;
17(10):e011471.
PMID: 39381880
Background: Women with heart failure and reduced ejection fraction (HFrEF) have greater symptoms and a lower quality of life compared with men; however, the role of noncardiac mechanisms remains poorly...
5.
Walker A, Watt N, Yuldasheva N, Dalmia S, Conning-Rowland M, Cheng C, et al.
Heliyon
. 2024 Sep;
10(16):e36457.
PMID: 39247377
Objective: Reduced IGF-1 signalling is an evolutionarily conserved mediator of longevity, yet the magnitude of this effect is substantially larger in organisms retaining a common insulin and IGF-1 receptor. Whether...
6.
Gierula J, Straw S, Cole C, Lowry J, Paton M, McGinlay M, et al.
Diab Vasc Dis Res
. 2024 Apr;
21(2):14791641231224241.
PMID: 38623877
Introduction: Type 2 diabetes is a common and adverse prognostic co-morbidity for patients with heart failure with reduced ejection fraction (HFrEF). The effect of diabetes on long-term outcomes for heart...
7.
Wood N, Straw S, Cheng C, Hirata Y, Pereira M, Gallagher H, et al.
Eur J Heart Fail
. 2024 Mar;
26(4):925-935.
PMID: 38468429
Aims: Patients with heart failure and reduced ejection fraction (HFrEF) exhibit skeletal muscle pathology, which contributes to symptoms and decreased quality of life. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) improve clinical...
8.
Javid R, Wassef N, Wheatcroft S, Tayebjee M
J Clin Med
. 2023 Nov;
12(22).
PMID: 38002591
Intracoronary guidewires used in percutaneous coronary intervention can also be configured to provide temporary ventricular pacing. Trans coronary electrophysiological parameters recorded by employing coronary guidewires may have a potential role...
9.
Brown O, Drozd M, McGowan H, Giannoudi M, Conning-Rowland M, Gierula J, et al.
Diabetes Care
. 2023 Jun;
46(8):1531-1540.
PMID: 37368983
Objective: Obesity and diabetes frequently coexist, yet their individual contributions to cardiovascular risk remain debated. We explored cardiovascular disease biomarkers, events, and mortality in the UK Biobank stratified by BMI...
10.
Chin C, Ravichandran R, Sanborn K, Fleming T, Wheatcroft S, Kearney M, et al.
Cell Rep Med
. 2023 Feb;
4(3):100945.
PMID: 36787736
Accumulation of senescent cells contributes to age-related diseases including idiopathic pulmonary fibrosis (IPF). Insulin-like growth factor binding proteins (IGFBPs) regulate many biological processes; however, the functional contributions of IGFBP2 in...