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Stephen A Udem

Explore the profile of Stephen A Udem including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
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Recent Articles
11.
Clarke D, Cooper D, Egan M, Hendry R, Parks C, Udem S
Springer Semin Immunopathol . 2006 Sep; 28(3):239-53. PMID: 16977404
Recombinant vesicular stomatitis virus (rVSV) is currently under evaluation as a human immunodeficiency virus (HIV)-1 vaccine vector. The most compelling reasons to develop rVSV as a vaccine vector include a...
12.
Natuk R, Cooper D, Guo M, Calderon P, Wright K, Nasar F, et al.
J Virol . 2006 Apr; 80(9):4447-57. PMID: 16611905
Recombinant vesicular stomatitis virus (rVSV) vectors offer an attractive approach for the induction of robust cellular and humoral immune responses directed against human pathogen target antigens. We evaluated rVSV vectors...
13.
Witko S, Kotash C, Nowak R, Johnson J, Boutilier L, Melville K, et al.
J Virol Methods . 2006 Mar; 135(1):91-101. PMID: 16569439
Recovery of recombinant, negative-strand, nonsegmented RNA viruses from a genomic cDNA clone requires a rescue system that promotes de novo assembly of a functional ribonucleoprotein (RNP) complex in the cell...
14.
Witko S, Kotash C, Sidhu M, Udem S, Parks C
Virology . 2006 Feb; 348(1):107-19. PMID: 16445957
Measles virus V protein is a Cys-rich polypeptide that is dispensable for virus propagation in continuous cell lines, but necessary for efficient viral replication in animals. Those functions modulating virus...
15.
Parks C, Witko S, Kotash C, Lin S, Sidhu M, Udem S
Virology . 2006 Jan; 348(1):96-106. PMID: 16442140
Measles virus V protein represses genome replication through a poorly understood mechanism, which led us to investigate whether V protein might be an RNA-binding modulatory factor. Recombinant V protein, expressed...
16.
Buonagurio D, Bechert T, Yang C, Shutyak L, DArco G, Kazachkov Y, et al.
Vaccine . 2006 Jan; 24(12):2151-60. PMID: 16413951
FluMist is a live-attenuated, trivalent influenza vaccine (LAIV) recently approved for intranasal administration. To demonstrate genetic stability during manufacture of the vaccine viruses in LAIV and a similar vaccine in...
17.
Buonagurio D, ONeill R, Shutyak L, DArco G, Bechert T, Kazachkov Y, et al.
Virology . 2006 Jan; 347(2):296-306. PMID: 16413592
The genetic and phenotypic stability of viruses isolated from young children following intranasal administration of the trivalent live-attenuated influenza virus vaccine (LAIV, marketed in the United States as FluMist) was...
18.
Lin Y, Deatly A, Chen W, Miller L, Lerch R, Sidhu M, et al.
Virus Res . 2005 Aug; 115(1):9-15. PMID: 16099066
An intranasally delivered, live attenuated, temperature sensitive (ts) respiratory syncytial virus vaccine candidate, rA2cp248/404/1,030DeltaSH, exhibits a low level of genetic instability in clinical studies, in contrast to the relatively high...
19.
Egan M, Chong S, Megati S, Montefiori D, Rose N, Boyer J, et al.
AIDS Res Hum Retroviruses . 2005 Aug; 21(7):629-43. PMID: 16060834
Of the various approaches being developed as prophylactic HIV vaccines, those based on a heterologous plasmid DNA prime, live vector boost vaccination regimen appear especially promising in the nonhuman primate/simian-human...
20.
Egan M, Chong S, Rose N, Megati S, Lopez K, Schadeck E, et al.
AIDS Res Hum Retroviruses . 2004 Dec; 20(9):989-1004. PMID: 15585086
An experimental AIDS vaccine based on attenuated, recombinant vesicular stomatitis virus (rVSV), when administered by a combination of parenteral and mucosal routes, has proven effective at preventing AIDS in a...