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Stephen A Coombes

Explore the profile of Stephen A Coombes including associated specialties, affiliations and a list of published articles. Areas
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Articles 80
Citations 1186
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Recent Articles
1.
Shin Y, Christensen D, Wang J, Shirley D, Orlando A, Romero R, et al.
Mol Autism . 2025 Mar; 16(1):16. PMID: 40050930
Background: Autism spectrum disorder (ASD) is a lifelong condition that profoundly impacts health, independence, and quality of life. However, research on brain aging in autistic adults is limited, and microstructural...
2.
Park J, Ho R, Wang W, Chiu S, Shin Y, Coombes S
Front Aging Neurosci . 2025 Mar; 17:1488811. PMID: 40040743
Advanced aging is associated with robust changes in neural activity. In addition to the well-established age-related slowing of the peak alpha frequency, there is a growing body of evidence showing...
3.
Jernigan J, Staley H, Baty Z, Bolen M, Gomes B, Holt J, et al.
J Neuroinflammation . 2025 Feb; 22(1):49. PMID: 39994765
Regulator of G-protein signaling 10 (RGS10), a key homeostatic regulator of immune cells, has been implicated in multiple diseases associated with aging and chronic inflammation including Parkinson's Disease (PD). Interestingly,...
4.
Jernigan J, Staley H, Baty Z, Bolen M, Gomes B, Holt J, et al.
bioRxiv . 2024 Nov; PMID: 39554164
Regulator of G-protein signaling 10 (RGS10), a key homeostatic regulator of immune cells, has been implicated in multiple diseases associated with aging and chronic inflammation including Parkinson's Disease (PD). Interestingly,...
5.
Wang W, Asken B, DeSimone J, Levy S, Barker W, Fiala J, et al.
Ageing Res Rev . 2024 Sep; 101:102507. PMID: 39306249
Neuroimaging and biofluid biomarkers provide a proxy of pathological changes for Alzheimer's disease (AD) and are useful in improving diagnosis and assessing disease progression. However, it is not clear how...
6.
Wang J, Christensen D, Coombes S, Wang Z
Neurosci Biobehav Rev . 2024 Jun; 163:105782. PMID: 38944227
Cognitive challenges and brain structure variations are common in autism spectrum disorder (ASD) but are rarely explored in middle-to-old aged autistic adults. Cognitive deficits that overlap between young autistic individuals...
7.
Park J, Ho R, Wang W, Nguyen V, Coombes S
Neuroimage . 2024 Apr; 292:120614. PMID: 38631618
With increasing age, peak alpha frequency (PAF) is slowed, and alpha power is reduced during resting-states with eyes closed. These age-related changes are evident across the whole scalp but remained...
8.
DeSimone J, Wang W, Loewenstein D, Duara R, Smith G, McFarland K, et al.
Alzheimers Dement . 2024 Mar; 20(4):2830-2842. PMID: 38441274
Introduction: Magnetic resonance imaging (MRI) biomarkers are needed for indexing early biological stages of Alzheimer's disease (AD), such as plasma amyloid-β (Aβ42/40) positivity in Aβ positron emission tomography (PET) negative...
9.
Ho R, Park J, Wang W, Thomas J, Cruz-Almeida Y, Coombes S
Pain . 2023 Dec; 165(5):1033-1043. PMID: 38112575
Significant progress has been made in linking measures of individual alpha frequency (IAF) and pain. A lower IAF has been associated with chronic neuropathic pain and with an increased sensitivity...
10.
Park J, Nguyen V, Ho R, Coombes S
Sci Rep . 2023 May; 13(1):7928. PMID: 37193730
Low back pain (LBP) has been associated with altered body sway during quiet standing, but the pattern of results is inconsistent. The purpose of this meta-analysis is to examine the...