Stephany Veuger
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Explore the profile of Stephany Veuger including associated specialties, affiliations and a list of published articles.
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10
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41
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Recent Articles
1.
Carter A, Veuger S, Racey S
J Vis Exp
. 2024 Mar;
(204).
PMID: 38465932
Cancer cells require large amounts of iron to maintain their proliferation. Iron metabolism is considered a hallmark of cancer, making iron a valid target for anti-cancer approaches. The development of...
2.
Nyong-Bassey E, Hicks A, Bergin P, Tuite E, Kozhevnikov V, Veuger S
Front Mol Biosci
. 2023 Nov;
10:1252285.
PMID: 37920709
Ruthenium(II) complexes have emerged recently as candidates for anti-cancer therapy, where activity is related to lipohilicity, cellular localization, and specific interactions with biomolecules. In this work, two novel complexes were...
3.
Mulligan E, Tudhope S, Hunter J, Clift A, Elliott S, Summerfield G, et al.
Cancers (Basel)
. 2023 Oct;
15(19).
PMID: 37835430
Background: Canonical NF-κB signalling by p65 (RelA) confers chemo-resistance and poor survival in chronic lymphocytic leukaemia (CLL). The role of non-canonical NF-κB signalling (leading to RelB and p52 subunit activation)...
4.
Abdelaal G, Carter A, Cheung W, Panayiotidis M, Racey S, Tetard D, et al.
Biomedicines
. 2023 Jul;
11(7).
PMID: 37509712
Anti-cancer therapy by iron chelation has been shown to inhibit many cellular processes including DNA replication, mitochondrial metabolism and oncogenic signalling pathways (e.g., EGFR). Iron chelator SK4 represents a double...
5.
Neatu R, Enekwa I, Thompson D, Schwalbe E, Fois G, Abdelaal G, et al.
Noncoding RNA
. 2022 Dec;
8(6).
PMID: 36548182
LncRNAs are involved in regulatory processes in the human genome, including gene expression. The rs35705950 SNP, previously associated with IPF, overlaps with the recently annotated lncRNA AC061979.1, a 1712 nucleotide...
6.
Abdelaal G, Carter A, Panayiotides M, Tetard D, Veuger S
Front Mol Biosci
. 2022 Oct;
9:1005092.
PMID: 36213122
Iron is an essential micronutrient due to its involvement in many cellular processes including DNA replication and OXPHOS. Tumors overexpress iron metabolism linked proteins which allow for iron accumulation driving...
7.
Kyriakou S, Cheung W, Mantso T, Mitsiogianni M, Anestopoulos I, Veuger S, et al.
Invest New Drugs
. 2021 Feb;
39(4):971-986.
PMID: 33624234
Melanoma is an aggressive and highly metastatic type of skin cancer where the design of new therapies is of utmost importance for the clinical management of the disease. Thus, we...
8.
Abdelaal G, Veuger S
Oncotarget
. 2021 Feb;
12(2):106-124.
PMID: 33520115
Cancer cells accumulate iron to supplement their aberrant growth and metabolism. Depleting cells of iron by iron chelators has been shown to be selectively cytotoxic to cancer cells and ....
9.
Kyriakou S, Mitsiogianni M, Mantso T, Cheung W, Todryk S, Veuger S, et al.
Invest New Drugs
. 2019 Jun;
38(3):621-633.
PMID: 31240512
The anticancer activity of a series of novel synthesized, hydroxypyridone-based metal chelators (analogues of L-mimosine) was evaluated in an in vitro model of melanoma consisting of malignant melanoma (A375), non-melanoma...
10.
Forgham H, Johnson D, Carter N, Veuger S, Carr-Wilkinson J
Front Cell Dev Biol
. 2015 Dec;
3:77.
PMID: 26697427
The prognostic value of cancer stem cell markers in various cancer subtypes is a well documented research area. Our findings show that the stem cell marker Lgr5 is associated with...