Stephanie Pfaender
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Explore the profile of Stephanie Pfaender including associated specialties, affiliations and a list of published articles.
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100
Citations
2213
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Recent Articles
1.
Awad N, Weidinger D, Greune L, Kronsbein J, Heinen N, Westhoven S, et al.
Cell Biol Toxicol
. 2024 Nov;
40(1):96.
PMID: 39538061
Background: Hypersensitivity to odorants like perfumes can induce or promote asthma with non-type 2 inflammation for which therapeutic options are limited. Cell death of primary bronchial epithelial cells (PBECs) and...
2.
Kuhn D, Heinen N, Sutter K, Herrmann S, Nocke M, Todt D, et al.
J Med Virol
. 2024 Sep;
96(10):e29935.
PMID: 39323094
Studies have pointed to a decisive role of autoantibodies in the context of sepsis and severe Coronavirus disease 2019 (COVID-19), which itself often fulfills the criteria for sepsis, including dysregulated...
3.
Herrmann A, Gege C, Wangen C, Wagner S, Kogler M, Cordsmeier A, et al.
Antiviral Res
. 2024 Sep;
231:106008.
PMID: 39306285
Host-directed antivirals (HDAs) represent an attractive treatment option and a strategy for pandemic preparedness, especially due to their potential broad-spectrum antiviral activity and high barrier to resistance development. Particularly, dual-targeting...
4.
Reichert I, Lee J, Weber L, Fuh M, Schlaeger L, Rossler S, et al.
PLoS Pathog
. 2024 Sep;
20(9):e1012509.
PMID: 39241103
The replication organelle of hepatitis C virus (HCV), called membranous web, is derived from the endoplasmic reticulum (ER) and mainly comprises double membrane vesicles (DMVs) that concentrate the viral replication...
5.
Khanal R, Heinen N, Bogomolova A, Meister T, Herrmann S, Westhoven S, et al.
Liver Int
. 2024 Aug;
44(11):2983-2995.
PMID: 39175256
Background And Aims: Severe acute respiratory syndrome coronavirus (SARS-CoV-2) preferentially infects the respiratory tract; however, several studies have implicated a multi-organ involvement. Hepatic dysfunctions caused by SARS-CoV-2 infection have been...
6.
Pfaender S, Steinmann E
Curr Opin Microbiol
. 2024 Aug;
81:102523.
PMID: 39098125
No abstract available.
7.
Qu B, Miskey C, Gomer A, Kleinert R, Ibanez S, Eberle R, et al.
Proc Natl Acad Sci U S A
. 2024 May;
121(23):e2407437121.
PMID: 38814864
The accessory protease transmembrane protease serine 2 (TMPRSS2) enhances severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uptake into ACE2-expressing cells, although how increased entry impacts downstream viral and host processes...
8.
Ziehe D, Wolf A, Rahmel T, Nowak H, Haberl H, Bergmann L, et al.
Front Immunol
. 2024 May;
15:1386586.
PMID: 38779663
Background: Sepsis, a life-threatening condition caused by the dysregulated host response to infection, is a major global health concern. Understanding the impact of viral or bacterial pathogens in sepsis is...
9.
Weidinger D, Jacobsen J, Alisch D, Uebner H, Heinen N, Greune L, et al.
Eur J Cell Biol
. 2024 Apr;
103(2):151408.
PMID: 38583306
Background: Therapeutic options for steroid-resistant non-type 2 inflammation in obstructive lung diseases are limited. Bronchial epithelial cells are key in the pathogenesis by releasing the central proinflammatory cytokine interleukine-8 (IL-8)....
10.
Heinen N, Klohn M, Westhoven S, Brown R, Pfaender S
Curr Opin Microbiol
. 2024 Mar;
79:102455.
PMID: 38522265
Hepatic sequelae are frequently reported in coronavirus disease 2019 cases and are correlated with increased disease severity. Therefore, a detailed exploration of host factors contributing to hepatic impairment and ultimately...