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» Authors » Stephanie N Kehlet

Stephanie N Kehlet

Explore the profile of Stephanie N Kehlet including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 4
Citations 59
Followers 0
Related Specialties
Oncology
General Medicine
Biochemistry
Top 10 Co-Authors
Nicholas Willumsen
Cecilie L Bager
Diana J Leeming
Anne-Christine Bay-Jensen
Katrine Dragsbaek
Claus Christiansen
Morten Karsdal
Morten A Karsdal
Henrik B Hansen
Henrik Harling
Published In
Cancer Epidemiol Biomarkers Prev
PLoS One
Oncol Lett
Oncotarget
Affiliations
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Recent Articles
1.
Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age- and sex-dependent remodeling of the extracellular matrix
Kehlet S, Willumsen N, Armbrecht G, Dietzel R, Brix S, Henriksen K, et al.
PLoS One . 2018 Mar; 13(3):e0194458. PMID: 29596429
The extracellular matrix (ECM) plays a vital role in maintaining normal tissue function. Collagens are major components of the ECM and there is a tight equilibrium between degradation and formation...
2.
Excessive matrix metalloprotease-mediated degradation of interstitial tissue (type I collagen) independently predicts short-term survival in an observational study of postmenopausal women diagnosed with cancer
Willumsen N, Bager C, Kehlet S, Dragsbaek K, Neergaard J, Hansen H, et al.
Oncotarget . 2017 Sep; 8(32):52501-52510. PMID: 28881747
Extensive tissue remodeling mediated by matrix metalloproteases (MMPs) is an important part of cancer. The aim of this study was to investigate whether serum biomarkers reflecting MMP-mediated degradation of type...
3.
Unique insight into microenvironmental changes in colorectal cancer: assessment of matrix metalloprotease-mediated molecular changes in human colorectal tumor tissue and corresponding non-neoplastic adjacent tissue
Willumsen N, Bager C, Bay-Jensen A, Kehlet S, Harling H, Leeming D, et al.
Oncol Lett . 2017 May; 13(5):3774-3780. PMID: 28529592
Matrix metalloprotease (MMP)-mediated tissue remodeling is one of the malignant changes driving colorectal cancer. Measurement of altered MMP expression/activity is not sufficient to fully understand the effect of MMP-mediated tissue...
4.
Remodeling of the Tumor Microenvironment Predicts Increased Risk of Cancer in Postmenopausal Women: The Prospective Epidemiologic Risk Factor (PERF I) Study
Bager C, Willumsen N, Kehlet S, Hansen H, Bay-Jensen A, Leeming D, et al.
Cancer Epidemiol Biomarkers Prev . 2016 Jul; 25(9):1348-55. PMID: 27411352
Background: An altered tumor microenvironment is one of the earliest signs of cancer and an important driver of the disease. We have seen previously that biomarkers reflecting tumor microenvironment modifications,...