Stephanie L Battle
Overview
Explore the profile of Stephanie L Battle including associated specialties, affiliations and a list of published articles.
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12
Citations
377
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Recent Articles
1.
Lake N, Ma K, Liu W, Battle S, Laricchia K, Tiao G, et al.
Nature
. 2024 Oct;
635(8038):390-397.
PMID: 39415008
Mitochondrial DNA (mtDNA) has an important yet often overlooked role in health and disease. Constraint models quantify the removal of deleterious variation from the population by selection and represent powerful...
2.
Harvey C, Weinreich M, Lee J, Shaw A, Ferraiuolo L, Mortiboys H, et al.
Heliyon
. 2024 Feb;
10(3):e24975.
PMID: 38317984
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving selective vulnerability of energy-intensive motor neurons (MNs). It has been unclear whether mitochondrial function is an upstream driver or a...
3.
Hong Y, Battle S, Shi W, Puiu D, Pillalamarri V, Xie J, et al.
Nat Commun
. 2023 Sep;
14(1):6113.
PMID: 37777527
Mitochondria carry their own circular genome and disruption of the mitochondrial genome is associated with various aging-related diseases. Unlike the nuclear genome, mitochondrial DNA (mtDNA) can be present at 1000 ...
4.
Hong Y, Battle S, Puiu D, Shi W, Pankratz N, Zhao D, et al.
Environ Health Perspect
. 2023 May;
131(5):57703.
PMID: 37192320
No abstract available.
5.
Battle S, Puiu D, Verlouw J, Broer L, Boerwinkle E, Taylor K, et al.
NAR Genom Bioinform
. 2022 May;
4(2):lqac034.
PMID: 35591888
Mitochondrial diseases are a heterogeneous group of disorders that can be caused by mutations in the nuclear or mitochondrial genome. Mitochondrial DNA (mtDNA) variants may exist in a state of...
6.
Yu B, Jayavelu N, Battle S, Mar J, Schimmel T, Cohen J, et al.
PLoS One
. 2020 Nov;
15(11):e0241698.
PMID: 33152014
Oocyte maturation is a coordinated process that is tightly linked to reproductive potential. A better understanding of gene regulation during human oocyte maturation will not only answer an important question...
7.
Yu B, Smith T, Battle S, Ferrell S, Hawkins R
Epigenetics
. 2019 May;
14(8):780-790.
PMID: 31060426
Assisted reproductive technologies are known to alter the developmental environment of gametes and early embryos during the most dynamic period of establishing the epigenome. This may result in the introduction...
8.
Battle S, Jayavelu N, Azad R, Hesson J, Ahmed F, Overbey E, et al.
Stem Cell Reports
. 2019 May;
12(5):1129-1144.
PMID: 31056477
During mammalian embryogenesis, changes in morphology and gene expression are concurrent with epigenomic reprogramming. Using human embryonic stem cells representing the preimplantation blastocyst (naive) and postimplantation epiblast (primed), our data...
9.
Pasumarthy K, Jayavelu N, Kilpinen L, Andrus C, Battle S, Korhonen M, et al.
Stem Cell Reports
. 2017 Aug;
9(3):999-1015.
PMID: 28844656
Human bone marrow stromal cells, or mesenchymal stem cells (BM-MSCs), need expansion prior to use as cell-based therapies in immunological and tissue repair applications. Aging and expansion of BM-MSCs induce...
10.
Valensisi C, Liao J, Andrus C, Battle S, Hawkins R
BMC Genomics
. 2015 Dec;
16:1083.
PMID: 26692029
Background: ChIP-seq is highly utilized for mapping histone modifications that are informative about gene regulation and genome annotations. For example, applying ChIP-seq to histone modifications such as H3K4me1 has facilitated...