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Stephanie Corgnac

Explore the profile of Stephanie Corgnac including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 1010
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Recent Articles
1.
Paolini L, Tran T, Corgnac S, Villemin J, Wislez M, Arrondeau J, et al.
J Immunother Cancer . 2024 Dec; 12(12. PMID: 39631852
Background: A high density of resident memory T cells (T) in tumors correlates with improved clinical outcomes in immunotherapy-treated patients. In most clinical studies, T are defined by the CD103...
2.
Broquet A, Gourain V, Goronflot T, Le Mabecque V, Sinha D, Ashayeripanah M, et al.
Nat Immunol . 2024 Oct; 25(11):2167. PMID: 39375552
No abstract available.
3.
Veith I, Nurmik M, Mencattini A, Damei I, Lansche C, Brosseau S, et al.
Cell Rep Med . 2024 May; 5(5):101549. PMID: 38703767
There is a compelling need for approaches to predict the efficacy of immunotherapy drugs. Tumor-on-chip technology exploits microfluidics to generate 3D cell co-cultures embedded in hydrogels that recapitulate simplified tumor...
4.
Broquet A, Gourain V, Goronflot T, Le Mabecque V, Sinha D, Ashayeripanah M, et al.
Nat Immunol . 2024 Apr; 25(5):802-819. PMID: 38684922
Sepsis induces immune alterations, which last for months after the resolution of illness. The effect of this immunological reprogramming on the risk of developing cancer is unclear. Here we use...
5.
Damei I, Trickovic T, Mami-Chouaib F, Corgnac S
Front Immunol . 2023 Aug; 14:1205984. PMID: 37545498
Tumor-infiltrating lymphocytes (TIL) often include a substantial subset of CD8 tissue-resident memory T (T) cells enriched in tumor-specific T cells. These T cells play a major role in antitumor immune...
6.
Ashi M, Mami-Chouaib F, Corgnac S
Explor Target Antitumor Ther . 2023 Jan; 3(6):746-762. PMID: 36654823
Major advances in cancer treatment have emerged with the introduction of immunotherapies using blocking antibodies that target T-cell inhibitory receptors, such as programmed death-1 (PD-1) and cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4),...
7.
Garcia-Pardo M, Gorria T, Malenica I, Corgnac S, Teixido C, Mezquita L
Vaccines (Basel) . 2022 May; 10(5). PMID: 35632496
Immunotherapy using immune checkpoint modulators has revolutionized the oncology field, emerging as a new standard of care for multiple indications, including non-small cell lung cancer (NSCLC). However, prognosis for patients...
8.
Corgnac S, Damei I, Gros G, Caidi A, Terry S, Chouaib S, et al.
J Immunother Cancer . 2022 Apr; 10(4). PMID: 35418483
Background: Cancer stem cells (CSC) define a population of rare malignant cells endowed with 'stemness' properties, such as self-renewing, multipotency and tumorigenicity. They are responsible for tumor initiation and progression,...
9.
Taoufik Y, de Goer de Herve M, Corgnac S, Durrbach A, Mami-Chouaib F
Front Immunol . 2021 Oct; 12:692598. PMID: 34630382
Since its emergence at the end of 2019, SARS-CoV-2 has spread worldwide at a very rapid pace. While most infected individuals have an asymptomatic or mild disease, a minority, mainly...
10.
Malenica I, Adam J, Corgnac S, Mezquita L, Auclin E, Damei I, et al.
Nat Commun . 2021 Sep; 12(1):5209. PMID: 34471106
TGF-β is secreted in the tumour microenvironment in a latent, inactive form bound to latency associated protein and activated by the integrin α subunit. The activation of latent TGF-β by...