Stephanie A Christenson
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Explore the profile of Stephanie A Christenson including associated specialties, affiliations and a list of published articles.
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71
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2295
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Recent Articles
1.
Orchard P, Blackwell T, Kachuri L, Castaldi P, Cho M, Christenson S, et al.
medRxiv
. 2025 Mar;
PMID: 40034763
Most genetic variants associated with complex traits and diseases occur in non-coding genomic regions and are hypothesized to regulate gene expression. To understand the genetics underlying gene expression variability, we...
2.
Vogelmeier C, Rabe K, Bhatt S, Hanania N, Bafadhel M, Christenson S, et al.
Respir Med
. 2025 Mar;
:108015.
PMID: 40024335
Background: The body mass index, airflow obstruction, dyspnea, and exercise capacity (BODE) index predicts 5-year mortality risk in chronic obstructive pulmonary disease (COPD); higher scores predict worse outcomes. Dupilumab, a...
3.
Celli B, Christenson S, Christenson S, Rabe K, Han M, van den Berge M, et al.
Am J Respir Crit Care Med
. 2025 Feb;
PMID: 39938077
Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition of the lungs, characterized by chronic respiratory symptoms, primarily dyspnea, cough, and sputum production, due to airway and/or alveoli abnormalities that...
4.
Bhatt S, Rabe K, Hanania N, Vogelmeier C, Bafadhel M, Christenson S, et al.
Lancet Respir Med
. 2025 Feb;
13(3):234-243.
PMID: 39900091
Background: Dupilumab, a fully human monoclonal antibody, blocks the shared receptor component for IL-4 and IL-13, which are key drivers of type 2 inflammation. We aimed to characterise the efficacy...
5.
Bhatt S, Rabe K, Hanania N, Vogelmeier C, Bafadhel M, Christenson S, et al.
Chest
. 2025 Feb;
PMID: 39894389
Background: Patient-reported outcomes should be considered alongside clinical assessments to guide therapy for COPD. Research Question: Does add-on dupilumab treatment improve health-related quality of life and respiratory symptoms in patients...
6.
Singh D, Brightling C, Rabe K, Han M, Christenson S, Drummond M, et al.
Lancet Respir Med
. 2024 Dec;
13(1):47-58.
PMID: 39653044
Background: Tezepelumab is a human monoclonal antibody that blocks thymic stromal lymphopoietin, which has shown increased expression in patients with chronic obstructive pulmonary disease (COPD) compared with healthy individuals. We...
7.
Bhatt S, Rabe K, Hanania N, Vogelmeier C, Bafadhel M, Christenson S, et al.
Respir Med
. 2024 Oct;
236():107846.
PMID: 39481660
Background: Dupilumab, a fully human monoclonal antibody that blocks the shared receptor component for interleukin-4 and interleukin-13, reduced exacerbations and improved lung function in patients with chronic obstructive pulmonary disease...
8.
Sciurba F, Christenson S, Rheault T, Bengtsson T, Rickard K, Barjaktarevic I
Chest
. 2024 Aug;
167(2):425-435.
PMID: 39197510
Background: Exacerbations in COPD can be life-threatening and can lead to irreversible declines in lung function and quality of life. Medications that reduce exacerbation burden are an unmet need, because...
9.
Curtis J, Bateman L, Murray S, Couper D, Labaki W, Freeman C, et al.
Chronic Obstr Pulm Dis
. 2024 Aug;
11(5):444-459.
PMID: 39159077
Background: The biological mechanisms leading some tobacco-exposed individuals to develop early-stage chronic obstructive pulmonary disease (COPD) are poorly understood. This knowledge gap hampers development of disease-modifying agents for this prevalent...
10.
Liegeois M, Braunreuther M, Charbit A, Raymond W, Tang M, Woodruff P, et al.
JCI Insight
. 2024 Jun;
9(15).
PMID: 38889046
Mucus plugs occlude airways to obstruct airflow in asthma. Studies in patients and in mouse models show that mucus plugs occur in the context of type 2 inflammation, and studies...