Stephane Loyau
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Explore the profile of Stephane Loyau including associated specialties, affiliations and a list of published articles.
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44
Citations
1040
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Recent Articles
1.
Dupont S, Lebas H, Mavouna S, Pascal E, Perrot A, Cogo A, et al.
J Am Heart Assoc
. 2025 Jan;
14(3):e034207.
PMID: 39818980
Background: Antiplatelet drugs represent potential candidates for protecting the penumbral microcirculation during cerebral ischemia and improving the benefits of arterial recanalization in ischemic stroke. Yet while the efficacy of such...
2.
Arocas V, Venisse L, Boulaftali Y, Loyau S, Flaujac C, de Raucourt E, et al.
Thromb Res
. 2024 Oct;
243:109174.
PMID: 39378567
No abstract available.
3.
Bourrienne M, Loyau S, Faille D, Gay J, Akhenak S, Farkh C, et al.
J Thromb Haemost
. 2024 Sep;
22(11):3199-3208.
PMID: 39260744
Background: Myeloproliferative neoplasms (MPNs) are characterized by a high rate of thrombotic complications that contribute to morbidity and mortality. MPN-related thrombogenesis is assumed to be multifactorial, involving both procoagulant and...
4.
Bourrienne M, Le Cam Duchez V, Faille D, Farkh C, Solo Nomenjanahary M, Gay J, et al.
Blood Adv
. 2024 Feb;
8(12):3330-3343.
PMID: 38386979
Cerebral venous sinus thrombosis (CVST) is an uncommon venous thromboembolic event accounting for <1% of strokes resulting in brain parenchymal injuries. JAK2V617F mutation, the most frequent driving mutation of myeloproliferative...
5.
High factor VIII concentrations interfere with glycoprotein VI-mediated platelet activation in vitro
Sekar R, Mimoun A, Bou-Jaoudeh M, Loyau S, Delignat S, Daventure V, et al.
J Thromb Haemost
. 2024 Feb;
22(5):1489-1495.
PMID: 38325597
Background: The recruitment of activated factor VIII (FVIII) at the surface of activated platelets is a key step toward the burst of thrombin and fibrin generation during thrombus formation at...
6.
Loyau S, Bauters A, Trillot N, Garcia C, Cougoul P, Pol H, et al.
Platelets
. 2023 Jun;
34(1):2226756.
PMID: 37350057
The association between endometriosis and autoimmune diseases is well known, however no acquired platelet function defect has been described so far. We describe the case of two patients with endometriosis...
7.
Doute M, Sannier A, Even G, Tran T, Gaston A, Delbosc S, et al.
J Am Soc Nephrol
. 2023 Apr;
34(7):1207-1221.
PMID: 37022108
Significance Statement: Kidney-derived thrombopoietin (TPO) increases myeloid cell and platelet production during antibody-mediated chronic kidney disease (AMCKD) in a mouse model, exacerbating chronic thromobinflammation in microvessels. The effect is mirrored...
8.
Billiald P, Slater A, Welin M, Clark J, Loyau S, Pugniere M, et al.
Blood Adv
. 2022 Nov;
7(7):1258-1268.
PMID: 36375047
Platelet glycoprotein VI (GPVI) is attracting interest as a potential target for the development of new antiplatelet molecules with a low bleeding risk. GPVI binding to vascular collagen initiates thrombus...
9.
Delvoye F, Loyau S, Labreuche J, Taylor G, Maier B, Piotin M, et al.
Platelets
. 2021 Apr;
33(2):285-290.
PMID: 33840346
Immediate reocclusion after mechanical thrombectomy (MT) for acute ischemic stroke (AIS) is a rare but devastating condition associated with poor functional outcome. The aim of this study was to gain...
10.
Bourrienne M, Loyau S, Benichi S, Gay J, Solo-Nomenjanahary M, Journe C, et al.
Transl Stroke Res
. 2021 Mar;
12(6):1055-1066.
PMID: 33675011
Cerebral venous sinus thrombosis (CVST) is an uncommon cause of stroke resulting in parenchymal injuries associated with heterogeneous clinical symptoms and prognosis. Therefore, an experimental animal model is required to...