Stephan Sigrist
Overview
Explore the profile of Stephan Sigrist including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
706
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Recent Articles
11.
Woznicka O, Gorlich A, Sigrist S, Pyza E
Front Cell Neurosci
. 2015 Jul;
9:238.
PMID: 26175667
In the first optic neuropil (lamina) of the optic lobe of Drosophila melanogaster, two classes of synapses, tetrad and feedback, show daily rhythms in the number and size of presynaptic...
12.
Stroedicke M, Bounab Y, Strempel N, Klockmeier K, Yigit S, Friedrich R, et al.
Genome Res
. 2015 Apr;
25(5):701-13.
PMID: 25908449
Assemblies of huntingtin (HTT) fragments with expanded polyglutamine (polyQ) tracts are a pathological hallmark of Huntington's disease (HD). The molecular mechanisms by which these structures are formed and cause neuronal...
13.
Eisenberg T, Schroeder S, Buttner S, Carmona-Gutierrez D, Pendl T, Andryushkova A, et al.
Autophagy
. 2014 Jun;
10(6):1143-5.
PMID: 24879160
The multifaceted process of aging inevitably leads to disturbances in cellular metabolism and protein homeostasis. To meet this challenge, cells make use of autophagy, which is probably one of the...
14.
Miskiewicz K, Jose L, Bento-Abreu A, Fislage M, Taes I, Kasprowicz J, et al.
Neuron
. 2011 Dec;
72(5):776-88.
PMID: 22153374
Elongator protein 3 (ELP3) acetylates histones in the nucleus but also plays a role in the cytoplasm. Here, we report that in Drosophila neurons, ELP3 is necessary and sufficient to...
15.
Knapek S, Sigrist S, Tanimoto H
J Neurosci
. 2011 Mar;
31(9):3453-8.
PMID: 21368057
In Drosophila, aversive associative memory of an odor consists of heterogeneous components with different stabilities. Here we report that Bruchpilot (Brp), a ubiquitous presynaptic active zone protein, is required for...
16.
Bahri S, Wang S, Conder R, Choy J, Vlachos S, Dong K, et al.
Development
. 2010 May;
137(12):2023-32.
PMID: 20501591
Dorsal closure (DC) of the Drosophila embryo is a model for the study of wound healing and developmental epithelial fusions, and involves the sealing of a hole in the epidermis...
17.
Leiss F, Koper E, Hein I, Fouquet W, Lindner J, Sigrist S, et al.
Dev Neurobiol
. 2009 Jan;
69(4):221-34.
PMID: 19160442
Dendritic spines are a characteristic feature of a number of neurons in the vertebrate nervous system and have been implicated in processes that include learning and memory. In spite of...
18.
Buttner S, Eisenberg T, Carmona-Gutierrez D, Ruli D, Knauer H, Ruckenstuhl C, et al.
Mol Cell
. 2007 Jan;
25(2):233-46.
PMID: 17244531
Endonuclease G (EndoG) is located in mitochondria yet translocates into the nucleus of apoptotic cells during human degenerative diseases. Nonetheless, a direct involvement of EndoG in cell-death execution remains equivocal,...
19.
Herker E, Jungwirth H, Lehmann K, Maldener C, Frohlich K, Wissing S, et al.
J Cell Biol
. 2004 Feb;
164(4):501-7.
PMID: 14970189
During the past years, yeast has been successfully established as a model to study mechanisms of apoptotic regulation. However, the beneficial effects of such a cell suicide program for a...