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Stephan Schultze-Strasser

Explore the profile of Stephan Schultze-Strasser including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 406
Followers 0
Related Specialties
General Medicine
Pharmacology
Pediatrics
Top 10 Co-Authors
Stefan Stein
Joachim Schwable
Manuel Grez
Christof von Kalle
Klaus Kuhlcke
Christoph Konigs
Manfred Schmidt
Ulrike Koehl
Dieter Hoelzer
Alwin Kramer
Published In
Nat Med
Front Pediatr
Pharm Unserer Zeit
PLoS One
Hum Gene Ther Clin Dev
Affiliations
Soon will be listed here.
Recent Articles
1.
Risk stratification integrating genetic data for factor VIII inhibitor development in patients with severe hemophilia A
Bachelet D, Albert T, Mbogning C, Hassler S, Zhang Y, Schultze-Strasser S, et al.
PLoS One . 2019 Jun; 14(6):e0218258. PMID: 31194850
Replacement therapy in severe hemophilia A leads to factor VIII (FVIII) inhibitors in 30% of patients. Factor VIII gene (F8) mutation type, a family history of inhibitors, ethnicity and intensity...
2.
An Exponential Regression Model Reveals the Continuous Development of B Cell Subpopulations Used as Reference Values in Children
Konigs C, Schultze-Strasser S, Quaiser A, Bochennek K, Schwabe D, Klingebiel T, et al.
Front Pediatr . 2018 May; 6:121. PMID: 29780793
B lymphocytes are key players in humoral immunity, expressing diverse surface immunoglobulin receptors directed against specific antigenic epitopes. The development and profile of distinct subpopulations have gained awareness in the...
3.
From bench to bedside: preclinical evaluation of a self-inactivating gammaretroviral vector for the gene therapy of X-linked chronic granulomatous disease
Stein S, Scholz S, Schwable J, Sadat M, Modlich U, Schultze-Strasser S, et al.
Hum Gene Ther Clin Dev . 2013 Jul; 24(2):86-98. PMID: 23845071
Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by impaired antimicrobial activity in phagocytic cells. As a monogenic disease affecting the hematopoietic system, CGD is amenable to gene therapy....
4.
[Gene therapy for septic granulomatosis: risks and opportunities. The road to successful treatment of congenital immunodeficiency]
Schwable J, Schultze-Strasser S, Stein S, Grez M
Pharm Unserer Zeit . 2011 Jun; 40(3):264-71. PMID: 21698616
No abstract available.
5.
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease
Stein S, Ott M, Schultze-Strasser S, Jauch A, Burwinkel B, Kinner A, et al.
Nat Med . 2010 Jan; 16(2):198-204. PMID: 20098431
Gene-modified autologous hematopoietic stem cells (HSC) can provide ample clinical benefits to subjects suffering from X-linked chronic granulomatous disease (X-CGD), a rare inherited immunodeficiency characterized by recurrent, often life-threatening bacterial...