Stephan Hardiville
Overview
Explore the profile of Stephan Hardiville including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
441
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Recent Articles
1.
Wreven E, Ruiz de Adana M, Hardiville S, Gmyr V, Kerr-Conte J, Chetboun M, et al.
Diabetologia
. 2025 Feb;
PMID: 39954060
No abstract available.
2.
Wreven E, Ruiz de Adana M, Hardiville S, Gmyr V, Kerr-Conte J, Chetboun M, et al.
Diabetologia
. 2024 Jun;
67(9):1877-1896.
PMID: 38864887
Aims/hypothesis: Insulitis, a hallmark of inflammation preceding autoimmune type 1 diabetes, leads to the eventual loss of functional beta cells. However, functional beta cells can persist even in the face...
3.
Very N, Hardiville S, Decourcelle A, Thevenet J, Djouina M, Page A, et al.
Oncogene
. 2021 Nov;
41(5):745-756.
PMID: 34845374
Alteration of O-GlcNAcylation, a dynamic posttranslational modification, is associated with tumorigenesis and tumor progression. Its role in chemotherapy response is poorly investigated. Standard treatment for colorectal cancer (CRC), 5-fluorouracil (5-FU),...
4.
Raab S, Gadault A, Very N, Decourcelle A, Baldini S, Schulz C, et al.
Cell Mol Life Sci
. 2021 May;
78(13):5397-5413.
PMID: 34046694
Fatty acid synthase (FASN) participates in many fundamental biological processes, including energy storage and signal transduction, and is overexpressed in many cancer cells. We previously showed in a context of...
5.
Kasprowicz A, Spriet C, Terryn C, Rigolot V, Hardiville S, Alteen M, et al.
Molecules
. 2020 Oct;
25(19).
PMID: 33019562
Monitoring glycosylation changes within cells upon response to stimuli remains challenging because of the complexity of this large family of post-translational modifications (PTMs). We developed an original tool, enabling labeling...
6.
Hardiville S, Banerjee P, Alpergin E, Smith D, Han G, Ma J, et al.
Mol Cell
. 2019 Dec;
77(5):1143-1152.e7.
PMID: 31866147
In eukaryotes, gene expression is performed by three RNA polymerases that are targeted to promoters by molecular complexes. A unique common factor, the TATA-box binding protein (TBP), is thought to...
7.
Gonzalez-Mariscal I, Montoro R, OConnell J, Kim Y, Gonzalez-Freire M, Liu Q, et al.
FASEB J
. 2019 Feb;
33(5):5850-5863.
PMID: 30726112
Sarcopenic obesity, the combination of skeletal muscle mass and function loss with an increase in body fat, is associated with physical limitations, cardiovascular diseases, metabolic stress, and increased risk of...
8.
Very N, Vercoutter-Edouart A, Lefebvre T, Hardiville S, El Yazidi-Belkoura I
Front Endocrinol (Lausanne)
. 2018 Oct;
9:602.
PMID: 30356686
The hexosamine biosynthetic pathway (HBP) and the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway are considered as nutrient sensors that regulate several essential biological processes. The hexosamine biosynthetic...
9.
Aquino-Gil M, Kupferschmid M, Shams-Eldin H, Schmidt J, Yamakawa N, Mortuaire M, et al.
Front Endocrinol (Lausanne)
. 2018 Sep;
9:450.
PMID: 30177911
-linked β-N-acetylglucosaminylation or -GlcNAcylation is a widespread post-translational modification that belongs to the large and heterogeneous group of glycosylations. The functions managed by -GlcNAcylation are diverse and include regulation of...
10.
Leturcq M, Mortuaire M, Hardiville S, Schulz C, Lefebvre T, Vercoutter-Edouart A
Cell Mol Life Sci
. 2018 Aug;
75(23):4321-4339.
PMID: 30069701
O-GlcNAcylation of proteins is governed by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). The homeostasis of O-GlcNAc cycling is regulated during cell cycle progression and is essential for proper cellular division....