Stella M K Glasauer
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Explore the profile of Stella M K Glasauer including associated specialties, affiliations and a list of published articles.
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12
Citations
572
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Recent Articles
1.
Niklaus S, Glasauer S, Kovermann P, Farshori K, Cadetti L, Fruh S, et al.
Open Biol
. 2024 Jul;
14(7):240140.
PMID: 39079673
In the central nervous system of vertebrates, glutamate serves as the primary excitatory neurotransmitter. However, in the retina, glutamate released from photoreceptors causes hyperpolarization in post-synaptic ON-bipolar cells through a...
2.
Almeida M, Eger S, He C, Audouard M, Nikitina A, Glasauer S, et al.
Neuron
. 2024 Feb;
112(11):1778-1794.e7.
PMID: 38417436
Highly penetrant autosomal dominant Alzheimer's disease (ADAD) comprises a distinct disease entity as compared to the far more prevalent form of AD in which common variants collectively contribute to risk....
3.
Bai Y, Camargo C, Glasauer S, Gifford R, Tian X, Longhini A, et al.
Nat Commun
. 2024 Jan;
15(1):350.
PMID: 38191490
Understanding metabolic heterogeneity is the key to uncovering the underlying mechanisms of metabolic-related diseases. Current metabolic imaging studies suffer from limitations including low resolution and specificity, and the model systems...
4.
Glasauer S, Goderie S, Rauch J, Guzman E, Audouard M, Bertucci T, et al.
Stem Cell Reports
. 2022 Aug;
17(9):2127-2140.
PMID: 35985329
Mutations in the MAPT gene that encodes tau lead to frontotemporal dementia (FTD) with pathology evident in both cerebral neurons and glia. Human cerebral organoids (hCOs) from individuals harboring pathogenic...
5.
Sharf T, van der Molen T, Glasauer S, Guzman E, Buccino A, Luna G, et al.
Nat Commun
. 2022 Jul;
13(1):4403.
PMID: 35906223
Human brain organoids replicate much of the cellular diversity and developmental anatomy of the human brain. However, the physiology of neuronal circuits within organoids remains under-explored. With high-density CMOS microelectrode...
6.
Karzbrun E, Khankhel A, Megale H, Glasauer S, Wyle Y, Britton G, et al.
Nature
. 2021 Oct;
599(7884):268-272.
PMID: 34707290
Understanding human organ formation is a scientific challenge with far-reaching medical implications. Three-dimensional stem-cell cultures have provided insights into human cell differentiation. However, current approaches use scaffold-free stem-cell aggregates, which...
7.
Glasauer S, Triemer T, Neef A, Neuhauss S, Luedtke N
Cell Chem Biol
. 2021 Sep;
28(11):1638-1647.e4.
PMID: 34592171
Asymmetric inheritance of sister chromatids has long been predicted to be linked to discordant fates of daughter cells and even hypothesized to minimize accumulation of mutations in stem cells. Here,...
8.
Schlegel D, Glasauer S, Mateos J, Barmettler G, Ziegler U, Neuhauss S
Invest Ophthalmol Vis Sci
. 2019 Dec;
60(15):5124-5135.
PMID: 31834350
Purpose: Mutations in CACNA2D4, encoding the α2δ4 subunit of retinal voltage-gated calcium channels (Cav), cause a rare type of retinal dysfunction in human, mainly affecting cone vision. Here, we investigate...
9.
Tera M, Glasauer S, Luedtke N
Chembiochem
. 2018 Jun;
19(18):1939-1943.
PMID: 29953711
Metabolic incorporation of bioorthogonal functional groups into cellular nucleic acids can be impeded by insufficient phosphorylation of nucleosides. Previous studies found that 5azidomethyl-2'-deoxyuridine (AmdU) was incorporated into the DNA of...
10.
Triemer T, Messikommer A, Glasauer S, Alzeer J, Paulisch M, Luedtke N
Proc Natl Acad Sci U S A
. 2018 Jan;
115(7):E1366-E1373.
PMID: 29378947
Many drugs require extensive metabolism en route to their targets. High-resolution visualization of prodrug metabolism should therefore utilize analogs containing a small modification that does not interfere with its metabolism...