Stella K Hur
Overview
Explore the profile of Stella K Hur including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
124
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Recent Articles
1.
Hur S, Somerville T, Wu X, Maia-Silva D, Demerdash O, Tuveson D, et al.
bioRxiv
. 2023 May;
PMID: 37131797
During the progression of pancreatic ductal adenocarcinoma (PDAC), tumor cells are known to acquire transcriptional and morphological properties of the basal (also known as squamous) epithelial lineage, which leads to...
2.
Chang S, Fulmer D, Hur S, Thorvaldsen J, Li L, Lan Y, et al.
Elife
. 2022 Nov;
11.
PMID: 36441651
Dysregulation of the imprinted locus can lead to Silver-Russell syndrome (SRS) in humans. However, the mechanism of how abnormal expression contributes to various SRS phenotypes remains unclear, largely due to...
3.
Chang S, Hur S, Naveh N, Thorvaldsen J, French D, Gagne A, et al.
Epigenetics
. 2020 Dec;
16(12):1295-1305.
PMID: 33300436
Genomic imprinting is a rare form of gene expression in mammals in which a small number of genes are expressed in a parent-of-origin-specific manner. The aetiology of human imprinting disorders...
4.
Somerville T, Xu Y, Wu X, Maia-Silva D, Hur S, de Almeida L, et al.
Proc Natl Acad Sci U S A
. 2020 May;
117(21):11471-11482.
PMID: 32385160
Lineage plasticity is a prominent feature of pancreatic ductal adenocarcinoma (PDA) cells, which can occur via deregulation of lineage-specifying transcription factors. Here, we show that the zinc finger protein ZBED2...
5.
Somerville T, Biffi G, Dassler-Plenker J, Hur S, He X, Vance K, et al.
Elife
. 2020 Apr;
9.
PMID: 32329713
A highly aggressive subset of pancreatic ductal adenocarcinomas undergo trans-differentiation into the squamous lineage during disease progression. Here, we investigated whether squamous trans-differentiation of human and mouse pancreatic cancer cells...
6.
Himes B, Obraztsova K, Lian L, Shumyatcher M, Rue R, Atochina-Vasserman E, et al.
PLoS One
. 2018 May;
13(5):e0197105.
PMID: 29758070
Lymphangioleiomyomatosis (LAM) is a rare, almost exclusively female lung disease linked to inactivating mutations in tuberous sclerosis complex 2 (TSC2), a tumor suppressor gene that controls cell metabolic state and...
7.
Freschi A, Hur S, Valente F, Ideraabdullah F, Sparago A, Gentile M, et al.
PLoS Genet
. 2018 Feb;
14(2):e1007243.
PMID: 29470501
Differential DNA methylation defects of H19/IGF2 are associated with congenital growth disorders characterized by opposite clinical pictures. Due to structural differences between human and mouse, the mechanisms by which mutations...
8.
Hur S, Freschi A, Ideraabdullah F, Thorvaldsen J, Luense L, Weller A, et al.
Proc Natl Acad Sci U S A
. 2016 Sep;
113(39):10938-43.
PMID: 27621468
Genomic imprinting affects a subset of genes in mammals, such that they are expressed in a monoallelic, parent-of-origin-specific manner. These genes are regulated by imprinting control regions (ICRs), cis-regulatory elements...