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Steffen Fuchs

Explore the profile of Steffen Fuchs including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 343
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Recent Articles
1.
Bessiere C, Meggetto F, Gaspin C, Fuchs S
Methods Mol Biol . 2025 Feb; 2880:49-68. PMID: 39900754
Circular RNAs are an emerging class of noncoding RNAs playing important functions in gene expression regulation. While different detection methods exist, the information of their full sequence remains more difficult...
2.
Grunewald L, Andersch L, Helmsauer K, Schwiebert S, Klaus A, Henssen A, et al.
Pharmacol Res . 2025 Jan; 212:107608. PMID: 39828101
Current treatment protocols have limited success against MYCN-amplified neuroblastoma. Adoptive T cell therapy presents an innovative strategy to improve cure rates. However, L1CAM-targeting CAR T cells achieved only limited response...
3.
Fuchs S, Danssmann C, Klironomos F, Winkler A, Fallmann J, Kruetzfeldt L, et al.
Nat Commun . 2023 Jul; 14(1):3936. PMID: 37402719
Circular RNAs (circRNAs) are a regulatory RNA class. While cancer-driving functions have been identified for single circRNAs, how they modulate gene expression in cancer is not well understood. We investigate...
4.
Fuchs S, Babin L, Andraos E, Bessiere C, Willier S, Schulte J, et al.
PLoS One . 2022 Sep; 17(9):e0273253. PMID: 36070299
Circular RNA (circRNA) is a noncoding RNA class with important implications for gene expression regulation, mostly by interaction with other RNA species or RNA-binding proteins. While the commonly applied short-read...
5.
Kural M, Jing J, Furbass F, Perko H, Qerama E, Johnsen B, et al.
Epilepsia . 2022 Feb; 63(5):1064-1073. PMID: 35184276
Objective: To evaluate the diagnostic performance of artificial intelligence (AI)-based algorithms for identifying the presence of interictal epileptiform discharges (IEDs) in routine (20-min) electroencephalography (EEG) recordings. Methods: We evaluated two...
6.
Babin L, Andraos E, Fuchs S, Pyronnet S, Brunet E, Meggetto F
JCI Insight . 2021 Nov; 6(21). PMID: 34747369
Circular RNAs (circRNAs) represent a type of endogenous noncoding RNA generated by back-splicing events. Unlike the majority of RNAs, circRNAs are covalently closed, without a 5' end or a 3'...
7.
Szymansky A, Kruetzfeldt L, Heukamp L, Hertwig F, Theissen J, Deubzer H, et al.
J Pers Med . 2021 Aug; 11(8). PMID: 34442335
For many years, the risk-based therapy stratification of children with neuroblastoma has relied on clinical and molecular covariates. In recent years, genome analysis has revealed further alterations defining risk, tumor...
8.
Kural M, Qerama E, Johnsen B, Fuchs S, Beniczky S
Clin Neurophysiol . 2021 May; 132(7):1543-1549. PMID: 34030055
Objective: The operational definition of interictal epileptiform discharges (IEDs) of the International Federation of Clinical Neurophysiology (IFCN) described six morphological criteria. Our objective was to assess the impact of pattern-repetition...
9.
Koche R, Rodriguez-Fos E, Helmsauer K, Burkert M, MacArthur I, Maag J, et al.
Nat Genet . 2020 Feb; 52(4):464. PMID: 32107479
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
10.
Koche R, Rodriguez-Fos E, Helmsauer K, Burkert M, MacArthur I, Maag J, et al.
Nat Genet . 2019 Dec; 52(1):29-34. PMID: 31844324
Extrachromosomal circularization of DNA is an important genomic feature in cancer. However, the structure, composition and genome-wide frequency of extrachromosomal circular DNA have not yet been profiled extensively. Here, we...