Stefano Menini
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Explore the profile of Stefano Menini including associated specialties, affiliations and a list of published articles.
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64
Citations
1886
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Recent Articles
1.
Haxhi J, Vitale M, Mattia L, Giuliani C, Sacchetti M, Orlando G, et al.
Front Endocrinol (Lausanne)
. 2024 Jun;
15:1393859.
PMID: 38854689
Background: Current guidelines for nonalcoholic fatty liver disease (NAFLD) recommend high volumes and/or intensities of physical activity (PA), the achievement of which generally requires participation in supervised exercise training programs...
2.
Iacobini C, Vitale M, Haxhi J, Menini S, Pugliese G
Cells
. 2024 May;
13(9.
PMID: 38727299
The adipose organ adapts and responds to internal and environmental stimuli by remodeling both its cellular and extracellular components. Under conditions of energy surplus, the subcutaneous white adipose tissue (WAT)...
3.
Iacobini C, Vitale M, Sentinelli F, Haxhi J, Pugliese G, Menini S
Int J Mol Sci
. 2024 Feb;
25(4).
PMID: 38396894
The (pro)renin receptor ((P)RR), a versatile protein found in various organs, including the kidney, is implicated in cardiometabolic conditions like diabetes, hypertension, and dyslipidemia, potentially contributing to organ damage. Importantly,...
4.
Casagrande V, Menini S, Interno C, Pugliese G, Federici M, Menghini R
Front Endocrinol (Lausanne)
. 2024 Feb;
14:1297847.
PMID: 38313841
Introduction: Type 1 diabetes mellitus (T1DM) development involves a complex interplay of genetic, environmental, and immunological factors. By modulating the activity of proteases and receptors, the protein tissue inhibitor of...
5.
Iacobini C, Vitale M, Pugliese G, Menini S
Front Oncol
. 2023 Jun;
13:1202093.
PMID: 37305566
The hypoxia-inducible factor-1α (HIF-1α), a key player in the adaptive regulation of energy metabolism, and the M2 isoform of the glycolytic enzyme pyruvate kinase (PKM2), a critical regulator of glucose...
6.
Iacobini C, Vitale M, Haxhi J, Pesce C, Pugliese G, Menini S
Antioxidants (Basel)
. 2022 Nov;
11(11).
PMID: 36358555
Oxidative stress and hypoxia-inducible factors (HIFs) have been implicated in the pathogenesis of diabetic cardiovascular and renal diseases. Reactive oxygen species (ROS) mediate physiological and pathophysiological processes, being involved in...
7.
Iacobini C, Vitale M, Haxhi J, Pesce C, Pugliese G, Menini S
Nutrients
. 2022 Mar;
14(5).
PMID: 35268036
Carbonyl stress is a condition characterized by an increase in the steady-state levels of reactive carbonyl species (RCS) that leads to accumulation of their irreversible covalent adducts with biological molecules....
8.
Iacobini C, Vitale M, Pugliese G, Menini S
Biomedicines
. 2021 Sep;
9(9).
PMID: 34572324
Intracellular metabolism of excess glucose induces mitochondrial dysfunction and diversion of glycolytic intermediates into branch pathways, leading to cell injury and inflammation. Hyperglycemia-driven overproduction of mitochondrial superoxide was thought to...
9.
Iacobini C, Vitale M, Pesce C, Pugliese G, Menini S
Antioxidants (Basel)
. 2021 Jun;
10(5).
PMID: 34063078
Twenty years have passed since Brownlee and colleagues proposed a single unifying mechanism for diabetic complications, introducing a turning point in this field of research. For the first time, reactive...
10.
Casagrande V, Iuliani G, Menini S, Pugliese G, Federici M, Menghini R
Clin Transl Med
. 2021 Feb;
11(2):e305.
PMID: 33634991
Background: Diabetic nephropathy (DN), one of the major complications of diabetes, is characterized by albuminuria, glomerulosclerosis, and progressive loss of renal function. Loss of TIMP3, an Extracellular Matrix bound protein...