Stefano E Rensi
Overview
Explore the profile of Stefano E Rensi including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
241
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0
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Recent Articles
1.
Bharat V, Durairaj A, Vanhauwaert R, Li L, Muir C, Chandra S, et al.
Cell Rep
. 2023 Dec;
42(12):113544.
PMID: 38060381
Dysregulated iron or Ca homeostasis has been reported in Parkinson's disease (PD) models. Here, we discover a connection between these two metals at the mitochondria. Elevation of iron levels causes...
2.
Song A, Rensi S, Tarquinio A, Cahan E, de Ruijter V, Wall J
Surg Innov
. 2022 Dec;
30(5):615-621.
PMID: 36511818
Background: Clinical trials represent a significant risk in the commercialization of surgical technologies. There is incentive for companies to mitigate their regulatory risk by targeting 510K over Premarket Approval (PMA)...
3.
Fecho K, Balhoff J, Bizon C, Byrd W, Hang S, Koslicki D, et al.
Clin Transl Sci
. 2021 Mar;
14(5):1719-1724.
PMID: 33742785
"Knowledge graphs" (KGs) have become a common approach for representing biomedical knowledge. In a KG, multiple biomedical data sets can be linked together as a graph representation, with nodes representing...
4.
Lo Y, Rensi S, Torng W, Altman R
Drug Discov Today
. 2018 May;
23(8):1538-1546.
PMID: 29750902
Chemoinformatics is an established discipline focusing on extracting, processing and extrapolating meaningful data from chemical structures. With the rapid explosion of chemical 'big' data from HTS and combinatorial synthesis, machine...
5.
Mallory E, Acharya A, Rensi S, Turnbaugh P, Bright R, Altman R
Pac Symp Biocomput
. 2017 Dec;
23:56-67.
PMID: 29218869
Bacteria in the human gut have the ability to activate, inactivate, and reactivate drugs with both intended and unintended effects. For example, the drug digoxin is reduced to the inactive...
6.
Rensi S, Altman R
J Chem Inf Model
. 2017 Jul;
57(8):1859-1867.
PMID: 28727421
Linear models offer a robust, flexible, and computationally efficient set of tools for modeling quantitative structure-activity relationships (QSARs) but have been eclipsed in performance by nonlinear methods. Support vector machines...