Stefano A Serapian
Overview
Explore the profile of Stefano A Serapian including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
32
Citations
199
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Mansoor S, Frasnetti E, Cucchi I, Magni A, Bonollo G, Serapian S, et al.
Cell Stress Chaperones
. 2025 Jan;
30(1):57-68.
PMID: 39884551
To carry out their functions in cells, proteins are required to fold into well-defined three-dimensional conformations. The stability of the folded state dictates several aspects of protein life, such as...
2.
Guerriere T, Vancheri A, Ricotti I, Serapian S, Eggerichs D, Tischler D, et al.
ACS Catal
. 2025 Jan;
15(2):1046-1060.
PMID: 39781101
Redox enzymes, mostly equipped with metal or organic cofactors, can vary their reactivity with oxygen by orders of magnitudes. Understanding how oxygen reactivity is controlled by the protein milieu remains...
3.
Scantamburlo F, Masgras I, Ciscato F, Laquatra C, Frigerio F, Cinquini F, et al.
J Chem Inf Model
. 2024 Oct;
64(21):8274-8282.
PMID: 39440601
The disruptive impact of the COVID-19 pandemic has led the scientific community to undertake an unprecedented effort to characterize viral infection mechanisms. Among these, interactions between the viral glycosylated Spike...
4.
Frasnetti E, Cucchi I, Pavoni S, Frigerio F, Cinquini F, Serapian S, et al.
J Chem Theory Comput
. 2024 Oct;
20(20):9209-9229.
PMID: 39387368
The modulation of protein function via designed small molecules is providing new opportunities in chemical biology and medicinal chemistry. While drugs have traditionally been developed to block enzymatic activities through...
5.
Frasnetti E, Magni A, Castelli M, Serapian S, Moroni E, Colombo G
Curr Opin Struct Biol
. 2024 May;
87:102835.
PMID: 38744148
Computational approaches can provide highly detailed insight into the molecular recognition processes that underlie drug binding, the assembly of protein complexes, and the regulation of biological functional processes. Classical simulation...
6.
Castelli M, Magni A, Bonollo G, Pavoni S, Frigerio F, Oliveira A, et al.
Protein Sci
. 2023 Dec;
33(3):e4880.
PMID: 38145386
Molecular chaperones, a family of proteins of which Hsp90 and Hsp70 are integral members, form an essential machinery to maintain healthy proteomes by controlling the folding and activation of a...
7.
Castelli M, Marchetti F, Osuna S, Oliveira A, Mulholland A, Serapian S, et al.
J Am Chem Soc
. 2023 Dec;
146(1):901-919.
PMID: 38116743
Protein functions are dynamically regulated by allostery, which enables conformational communication even between faraway residues, and expresses itself in many forms, akin to different "languages": allosteric control pathways predominating in...
8.
Mobili R, La Cognata S, Monteleone M, Longo M, Fuoco A, Serapian S, et al.
Chemistry
. 2023 Jul;
29(56):e202301437.
PMID: 37433050
The synthesis and characterization of a novel film-forming organic cage and of its smaller analogue are here described. While the small cage produced single crystals suitable for X-ray diffraction studies,...
9.
Casali E, Serapian S, Gianquinto E, Castelli M, Bertinaria M, Spyrakis F, et al.
Int J Biol Macromol
. 2023 Jul;
246:125609.
PMID: 37394218
The protein NLRP3 and its complexes are associated with an array of inflammatory pathologies, among which neurodegenerative, autoimmune, and metabolic diseases. Targeting the NLRP3 inflammasome represents a promising strategy for...
10.
Triveri A, Casali E, Frasnetti E, Doria F, Frigerio F, Cinquini F, et al.
J Chem Theory Comput
. 2023 Mar;
19(7):2120-2134.
PMID: 36926878
SARS-CoV-2 has evolved rapidly in the first 3 years of pandemic diffusion. The initial evolution of the virus appeared to proceed through big jumps in sequence changes rather than through...