Stefanie Engert
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Explore the profile of Stefanie Engert including associated specialties, affiliations and a list of published articles.
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13
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1104
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Recent Articles
1.
Shiu P, Sterne G, Engert S, Dickson B, Scott K
Elife
. 2022 Jul;
11.
PMID: 35791902
Taste detection and hunger state dynamically regulate the decision to initiate feeding. To study how context-appropriate feeding decisions are generated, we combined synaptic resolution circuit reconstruction with targeted genetic access...
2.
Engert S, Sterne G, Bock D, Scott K
Elife
. 2022 May;
11.
PMID: 35611959
Gustatory sensory neurons detect caloric and harmful compounds in potential food and convey this information to the brain to inform feeding decisions. To examine the signals that gustatory neurons transmit...
3.
Li H, Janssens J, De Waegeneer M, Kolluru S, Davie K, Gardeux V, et al.
Science
. 2022 Mar;
375(6584):eabk2432.
PMID: 35239393
For more than 100 years, the fruit fly has been one of the most studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula , that...
4.
Rebbeck T, Friebel T, Friedman E, Hamann U, Huo D, Kwong A, et al.
Hum Mutat
. 2018 Feb;
39(5):593-620.
PMID: 29446198
The prevalence and spectrum of germline mutations in BRCA1 and BRCA2 have been reported in single populations, with the majority of reports focused on White in Europe and North America....
5.
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer
Rebbeck T, Mitra N, Wan F, Healey S, McGuffog L, Chenevix-Trench G, et al.
JAMA
. 2015 Apr;
313(13):1347-61.
PMID: 25849179
Importance: Limited information about the relationship between specific mutations in BRCA1 or BRCA2 (BRCA1/2) and cancer risk exists. Objective: To identify mutation-specific cancer risks for carriers of BRCA1/2. Design, Setting,...
6.
Schnurbein G, Hauke J, Wappenschmidt B, Weber-Lassalle N, Engert S, Hellebrand H, et al.
Breast Cancer Res
. 2013 Dec;
15(6):R120.
PMID: 24359560
RAD51C is an integral part of the DNA double-strand repair through homologous recombination, and monoallelic mutations were found in ~1.3% of BRCA1/2-negative breast cancer (BC) and/or ovarian cancer (OC) families....
7.
Couch F, Wang X, McGuffog L, Lee A, Olswold C, Kuchenbaecker K, et al.
PLoS Genet
. 2013 Apr;
9(3):e1003212.
PMID: 23544013
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom...
8.
Wappenschmidt B, Becker A, Hauke J, Weber U, Engert S, Kohler J, et al.
PLoS One
. 2012 Dec;
7(12):e50800.
PMID: 23239986
Screening for pathogenic mutations in breast and ovarian cancer genes such as BRCA1/2, CHEK2 and RAD51C is common practice for individuals from high-risk families. However, test results may be ambiguous...
9.
Gaudet M, Kirchhoff T, Green T, Vijai J, Korn J, Guiducci C, et al.
PLoS Genet
. 2010 Nov;
6(10):e1001183.
PMID: 21060860
The considerable uncertainty regarding cancer risks associated with inherited mutations of BRCA2 is due to unknown factors. To investigate whether common genetic variants modify penetrance for BRCA2 mutation carriers, we...
10.
Sadr-Nabavi A, Ramser J, Volkmann J, Naehrig J, Wiesmann F, Betz B, et al.
Int J Cancer
. 2008 Dec;
124(7):1727-35.
PMID: 19115204
EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1) was recently described as an antagonist of angiogenesis. Motivated by a strong dependence of tumor growth and metastasis on angiogenesis, we investigated the...