Stefanie E Grund
Overview
Explore the profile of Stefanie E Grund including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
194
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Recent Articles
1.
Polycarpou-Schwarz M, Gross M, Mestdagh P, Schott J, Grund S, Hildenbrand C, et al.
Oncogene
. 2018 May;
37(34):4750-4768.
PMID: 29765154
Breast cancer is a leading cause of cancer-related death in women. Small open reading frame (sORF)-encoded proteins or microproteins constitute a new class of molecules often transcribed from presumed long...
2.
Link S, Grund S, Diederichs S
Nucleic Acids Res
. 2016 May;
44(11):5330-43.
PMID: 27185895
The RNase III enzyme Drosha is a key factor in microRNA (miRNA) biogenesis and as such indispensable for cellular homeostasis and developmental processes. Together with its co-factor DGCR8, it converts...
3.
Grund S, Polycarpou-Schwarz M, Luo C, Eichmuller S, Diederichs S
Neoplasia
. 2012 Apr;
14(3):238-48.
PMID: 22496623
Drosha is a key enzyme in microRNA biogenesis, generating the precursor miRNA (pre-miRNA) by excising the stem-loop embedded in the primary transcripts (pri-miRNA). The specificity for the pri-miRNAs and determination...
4.
Grund S, Fischer T, Cabal G, Antunez O, Perez-Ortin J, Hurt E
J Cell Biol
. 2008 Sep;
182(5):897-910.
PMID: 18762579
Inner nuclear membrane proteins containing a LEM (LAP2, emerin, and MAN1) domain participate in different processes, including chromatin organization, gene expression, and nuclear envelope biogenesis. In this study, we identify...