Stefan Zwirner
Overview
Explore the profile of Stefan Zwirner including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
182
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0
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Recent Articles
1.
Zwirner S, Abu Rmilah A, Klotz S, Pfaffenroth B, Kloevekorn P, Moschopoulou A, et al.
Cell
. 2024 Mar;
187(7):1666-1684.e26.
PMID: 38490194
Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver...
2.
Rudalska R, Harbig J, Snaebjornsson M, Klotz S, Zwirner S, Taranets L, et al.
Nat Cancer
. 2022 Feb;
2(2):201-217.
PMID: 35122079
The success of molecular therapies targeting specific metabolic pathways in cancer is often limited by the plasticity and adaptability of metabolic networks. Here we show that pharmacologically induced lipotoxicity represents...
3.
Koch M, Czemmel S, Lennartz F, Beyeler S, Rajaraman S, Przystal J, et al.
Neurooncol Adv
. 2020 Nov;
2(1):vdaa115.
PMID: 33134924
Background: The overexpression of (basic)helix-loop-helix ((b)HLH) transcription factors (TFs) is frequent in malignant glioma. We investigated molecular effects upon disruption of the (b)HLH network by a dominant-negative variant of the...
4.
Brenner E, Schorg B, Ahmetlic F, Wieder T, Hilke F, Simon N, et al.
Nat Commun
. 2020 Mar;
11(1):1335.
PMID: 32165639
Immune checkpoint blockade (ICB)-based or natural cancer immune responses largely eliminate tumours. Yet, they require additional mechanisms to arrest those cancer cells that are not rejected. Cytokine-induced senescence (CIS) can...
5.
Gresch G, Schenke L, Mladenov R, Zwirner S, Cremer C, Niesen J, et al.
Br J Haematol
. 2017 Oct;
183(2):313-317.
PMID: 29048126
No abstract available.
6.
Boege Y, Malehmir M, Healy M, Bettermann K, Lorentzen A, Vucur M, et al.
Cancer Cell
. 2017 Sep;
32(3):342-359.e10.
PMID: 28898696
Concomitant hepatocyte apoptosis and regeneration is a hallmark of chronic liver diseases (CLDs) predisposing to hepatocellular carcinoma (HCC). Here, we mechanistically link caspase-8-dependent apoptosis to HCC development via proliferation- and...