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Stefan Weidt

Explore the profile of Stefan Weidt including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 435
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Recent Articles
1.
Cortada-Garcia J, Haggarty J, Weidt S, Daly R, Arnold S, Burgess K
Biotechnol Bioeng . 2023 Nov; 121(2):683-695. PMID: 37990977
Fermentation monitoring is a powerful tool for bioprocess development and optimization. On-line metabolomics is a technology that is starting to gain attention as a bioprocess monitoring tool, allowing the direct...
2.
Rubic I, Weidt S, Burchmore R, Kovacevic A, Kules J, Eckersall P, et al.
Int J Mol Sci . 2023 Oct; 24(20). PMID: 37894863
Dilated cardiomyopathy is one of the important diseases in dogs and humans. The second most common cause of heart failure in dogs is idiopathic dilated cardiomyopathy (iDCM), which results in...
3.
McBride R, Wandy J, Weidt S, Rogers S, Davies V, Daly R, et al.
Bioinformatics . 2023 Jun; 39(7). PMID: 37364005
Motivation: Liquid Chromatography Tandem Mass Spectrometry experiments aim to produce high-quality fragmentation spectra, which can be used to annotate metabolites. However, current Data-Dependent Acquisition approaches may fail to collect spectra...
4.
Wandy J, McBride R, Rogers S, Terzis N, Weidt S, van der Hooft J, et al.
Front Mol Biosci . 2023 Mar; 10:1130781. PMID: 36959982
Data-Dependent and Data-Independent Acquisition modes (DDA and DIA, respectively) are both widely used to acquire MS2 spectra in untargeted liquid chromatography tandem mass spectrometry (LC-MS/MS) metabolomics analyses. Despite their wide...
5.
Nguyen T, Agazzi A, McGill S, Weidt S, Perricone V, Han Q, et al.
J Proteomics . 2022 Oct; 270:104740. PMID: 36191802
This study examines whether maternal low ω6:ω3 ratio diet and offspring SW supplementation can improve offspring immunity and performance by elucidating the effects on piglet serum proteome. A total of...
6.
Nguyen T, Agazzi A, McGill S, Weidt S, Han Q, Gelemanovic A, et al.
J Proteomics . 2022 Sep; 270:104739. PMID: 36174954
This study evaluates how long-term dietary low ω6:ω3 ratio in sows and offspring's seaweed (SW) intake affects piglet intestinal function and growth through modifying ileum proteome. Sows were assigned to...
7.
Nguyen T, Agazzi A, McGill S, Weidt S, Han Q, Gelemanovic A, et al.
J Proteomics . 2022 Mar; 260:104562. PMID: 35314360
This study aimed to investigate the characteristic proteomic pattern of plasma from sows supplemented with low dietary ω6:ω3 fatty acids (FAs) ratio during gestation and lactation. Two dietary treatments (n ...
8.
Meewan J, Somani S, Laskar P, Irving C, Mullin M, Woods S, et al.
Pharmaceutics . 2022 Feb; 14(2). PMID: 35214171
The formation of a protein layer "corona" on the nanoparticle surface upon entry into a biological environment was shown to strongly influence the interactions with cells, especially affecting the uptake...
9.
Rubic I, Burchmore R, Weidt S, Regnault C, Kules J, Baric Rafaj R, et al.
Int J Mol Sci . 2022 Feb; 23(3). PMID: 35163517
Canine babesiosis is an important tick-borne disease worldwide, caused by parasites of the genus. Although the disease process primarily affects erythrocytes, it may also have multisystemic consequences. The goal of...
10.
Davies V, Wandy J, Weidt S, van der Hooft J, Miller A, Daly R, et al.
Anal Chem . 2021 Mar; 93(14):5676-5683. PMID: 33784814
Tandem mass spectrometry (LC-MS/MS) is widely used to identify unknown ions in untargeted metabolomics. Data-dependent acquisition (DDA) chooses which ions to fragment based upon intensities observed in MS1 survey scans...