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Stefan Stremitzer

Explore the profile of Stefan Stremitzer including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 406
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Recent Articles
11.
Stift J, Graf A, Schwarz C, Tamandl D, Starlinger P, Herac M, et al.
Eur J Surg Oncol . 2017 Dec; 44(1):139-147. PMID: 29203074
Background: The value of microscopic biliary and perineural invasion as prognostic biomarkers in patients with resectable colorectal liver metastases (CLM) who undergo neoadjuvant chemotherapy and liver resection is still unclear....
12.
Haegele S, Reiter S, Wanek D, Offensperger F, Pereyra D, Stremitzer S, et al.
PLoS One . 2016 Nov; 11(11):e0165481. PMID: 27812143
Background: Postoperative liver dysfunction may lead to morbidity and mortality after liver resection. Preoperative liver function assessment is critical to identify preexisting liver dysfunction in patients prior to resection. The...
13.
Stremitzer S, Zhang W, Yang D, Ning Y, Sunakawa Y, Matsusaka S, et al.
Mol Cancer Ther . 2016 Aug; 15(11):2814-2821. PMID: 27535973
Angiogenesis-related gene expression is associated with the efficacy of anti-VEGF therapy. We tested whether intratumoral mRNA expression levels of genes involved in vascular morphogenesis and early vessel maturation predict response,...
14.
Okazaki S, Loupakis F, Stintzing S, Cao S, Zhang W, Yang D, et al.
Mol Cancer Ther . 2016 May; 15(7):1740-5. PMID: 27196764
The purpose of this study was to evaluate the clinical significance of single-nucleotide polymorphisms in TLR1, TLR2, TLR6, and TAK1 in patients with metastatic colorectal cancer (mCRC). We genotyped 9...
15.
Ning Y, Hanna D, Zhang W, Mendez A, Yang D, El-Khoueiry R, et al.
Mol Cancer Ther . 2015 Aug; 14(10):2401-8. PMID: 26227487
Circulating tumor cells (CTC) express epithelial and stem cell-like genes, though current approved detection methods mainly use epithelial markers. We optimized a CTC isolation method that could capture their molecular...
16.
Stintzing S, Zhang W, Heinemann V, Neureiter D, Kemmerling R, Kirchner T, et al.
Mol Cancer Ther . 2015 Jul; 14(10):2374-81. PMID: 26206335
Transmembrane receptors, such as the EGFR, are regulated by their turnover, which is dependent on the ubiquitin-proteasome system. We tested in two independent study cohorts whether SNPs in genes involved...
17.
Stremitzer S, Zhang W, Yang D, Ning Y, Stintzing S, Sebio A, et al.
Cancer . 2015 Feb; 121(11):1898-905. PMID: 25690670
Background: Genes involved in the angiopoietin and pericyte pathways may become escape mechanisms under antivascular endothelial growth factor (anti-VEGF) therapy. The authors investigated whether variations within genes in these pathways...
18.
Stintzing S, Stremitzer S, Sebio A, Lenz H
Hematol Oncol Clin North Am . 2014 Dec; 29(1):43-60. PMID: 25475572
This article clarifies prognostic and predictive markers in the treatment of colorectal cancer. Multiple chemotherapeutic drugs are approved for metastatic colorectal cancer (mCRC), but available guidelines are often not helpful...
19.
Sebio A, Gerger A, Matsusaka S, Yang D, Zhang W, Stremitzer S, et al.
Pharmacogenet Genomics . 2014 Nov; 25(1):30-7. PMID: 25379721
Objective: Obesity is an established risk factor for colorectal cancer (CRC) incidence and it is also linked to CRC recurrence and survival. Polymorphisms located in obesity-related genes are associated with...
20.
Stremitzer S, Stift J, Graf A, Singh J, Starlinger P, Gruenberger B, et al.
Ann Surg Oncol . 2014 Oct; 22(4):1315-23. PMID: 25323471
Background: Liver resection after neoadjuvant chemotherapy offers the chance of cure and long-term survival in patients with resectable colorectal liver metastases (CLM). Currently, there are no established biomarkers that could...