Stefan Schmitt
Overview
Explore the profile of Stefan Schmitt including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
394
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0
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Recent Articles
1.
Mark K, Kolla S, Aguirre J, Garshott D, Schmitt S, Haakonsen D, et al.
Cell
. 2023 Sep;
186(19):4252-4253.
PMID: 37714136
No abstract available.
2.
Mark K, Kolla S, Aguirre J, Garshott D, Schmitt S, Haakonsen D, et al.
Cell
. 2023 Jul;
186(16):3460-3475.e23.
PMID: 37478862
All eukaryotes require intricate protein networks to translate developmental signals into accurate cell fate decisions. Mutations that disturb interactions between network components often result in disease, but how the composition...
3.
Tsai J, Aguirre J, Li Y, Brown J, Focht V, Kater L, et al.
Mol Cell
. 2023 Jul;
83(15):2753-2767.e10.
PMID: 37478846
Nuclear hormone receptors (NRs) are ligand-binding transcription factors that are widely targeted therapeutically. Agonist binding triggers NR activation and subsequent degradation by unknown ligand-dependent ubiquitin ligase machinery. NR degradation is...
4.
Jahanbakhsh S, Hare J, Meister H, Ingesson C, Majewski M, Penzel F, et al.
Rev Sci Instrum
. 2023 Apr;
94(3):033503.
PMID: 37012795
For over 10 years, several bolometer sensors with different properties have been tested in the IBOVAC facility. The aim has been to develop a bolometer sensor that can be operated...
5.
Schmitt S, Hendlich M, Klebe G
Angew Chem Int Ed Engl
. 2018 May;
40(17):3141-3144.
PMID: 29712060
Protein function is almost invariably linked with the specific recognition of substrates or endogenous ligands in particular binding pockets; proteins of related function should, therefore, share comparable recognition pockets. On...
6.
Schmitt S, Baumgarten M, Simon J, Hafner K
Angew Chem Int Ed Engl
. 2018 May;
37(8):1077-1081.
PMID: 29711030
Simply mixing solutions of the title compound 1 and tetrathiafulvene (TTF) in acetonitrile provides the charge-transfer complex 2. Here, 1 functions as a novel electron acceptor and is present in...
7.
Nissink J, Schmitt S, Blackburn S, Peters S
J Biomol Screen
. 2013 Aug;
19(3):369-78.
PMID: 23918919
Customized compound picking and plating of very large corporate screening decks (many 100,000s) for high-throughput screening is generally restricted, both from a time and cost perspective. Here we present a...
8.
Gunther S, Danhardt S, Ehrensperger M, Zeller P, Schmitt S, Wintterlin J
ACS Nano
. 2012 Dec;
7(1):154-64.
PMID: 23214506
The ordering transition of an amorphous carbon layer into graphene was investigated by high-temperature scanning tunneling microscopy. A disordered C layer was prepared on a Ru(0001) surface by chemical vapor...
9.
Schmitt S, Bertsch U, Hose D, Goldschmidt H
Srp Arh Celok Lek
. 2012 Feb;
139 Suppl 2:90-4.
PMID: 22352189
The treatment approach in patients with multiple myeloma (MM) has been essentially changed with introduction of novel agents such as thalidomide, bortezomib and lenalidomide. In patients eligible for autologous stem...
10.
Krasowski A, Muthas D, Sarkar A, Schmitt S, Brenk R
J Chem Inf Model
. 2011 Oct;
51(11):2829-42.
PMID: 21995295
Judging if a protein is able to bind orally available molecules with high affinity, i.e. if a protein is druggable, is an important step in target assessment. In order to...