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Stefan Pierzynowski

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Articles 26
Citations 222
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Recent Articles
1.
Donaldson J, Jacek T, Wychowanski P, Zaworski K, Szkopek D, Wolinski J, et al.
Int J Mol Sci . 2025 Mar; 26(5). PMID: 40076444
Two different diets able to induce dietary hyperammonaemia (a methionine-choline-deficient (MCD) diet and a methionine-deficient diet enriched with ammonium acetate (MAD + 20% ammonium acetate)) were tested in a rat...
2.
Zaworski K, Wychowanski P, Szkopek D, Wolinski J, Donaldson J, Pierzynowski S, et al.
Int J Mol Sci . 2025 Jan; 26(1. PMID: 39796104
The aim of this study was to elucidate the impact of porcine pancreatic enzymes (Creon pancrelipase) in comparison to microbial-derived alpha amylase (MD amylase) on the small intestine wall structure,...
3.
Pierzynowska K, Zaworski K, Wychowanski P, Donaldson J, Wolinski J, Borowitz D, et al.
Biol Methods Protoc . 2024 Nov; 9(1):bpae078. PMID: 39512855
Protein maldigestion and malabsorption lead to malnutrition and are a feature of exocrine pancreatic insufficiency (EPI). Although it is the current standard, measurement of nitrogen in stool to assess protease...
4.
Pierzynowska K, Wychowanski P, Zaworski K, Wolinski J, Donaldson J, Pierzynowski S
Int J Mol Sci . 2023 Nov; 24(22). PMID: 38003366
The acini-islet-acinar (AIA) axis concept justifies the anatomical placement of the Langerhans islets within the exocrine pancreatic parenchyma and explains the existence of the pancreas as a single organ. Amylase...
5.
Freedman S, Zaworski K, Pierzynowska K, Pierzynowski S, Gallotto R, Sathe M, et al.
PLoS One . 2023 May; 18(5):e0284651. PMID: 37155649
Introduction: The coefficient of fat absorption (CFA) quantifies fat that remains in stool after digestion and is not a direct measure of lipolysis. CFA has been used to assess treatment...
6.
Zaworski K, Wolinski J, Slupecka-Ziemilska M, Pierzynowski S, Pierzynowska K
PLoS One . 2022 Mar; 17(3):e0265144. PMID: 35294477
Preterm birth is associated with increased risk of complications, specifically with regards to the gastrointestinal tract. These complications mainly include the maldigestion and malabsorption of nutrients resulting from the immaturity...
7.
Pierzynowski S, Pierzynowska K
Adv Med Sci . 2022 Mar; 67(1):142-147. PMID: 35245838
Purpose: Nitrogen (N) is an indispensable metabolite required for the synthesis of protein. In animals, gut bacteria and, to a certain extent, even hepatocytes, are able to assimilate nitrogen from...
8.
Pierzynowska K, Deshpande A, Mosiichuk N, Terkeltaub R, Szczurek P, Salido E, et al.
Front Med (Lausanne) . 2020 Dec; 7:569215. PMID: 33330529
Limitations in efficacy and/or tolerance of currently available urate-lowering therapies (ULTs), such as oral xanthine oxidase inhibitors, uricosurics, and intravenous uricase agents contribute to the development of refractory gout. Renal...
9.
Pierzynowska K, Oredsson S, Pierzynowski S
J Diabetes Res . 2020 Dec; 2020:2148740. PMID: 33294459
The current study was aimed at highlighting the role of blood pancreatic amylase in the regulation of glucose homeostasis and insulin secretion in a porcine model of streptozotocin- (STZ-) induced...
10.
Pierzynowska K, Lozinska L, Wolinski J, Pierzynowski S
PLoS One . 2018 Jun; 13(6):e0198672. PMID: 29874296
The purpose of this research is to explore the link between plasma amylase and insulin levels in growing pigs. Blood was obtained from piglets ranging in age from preterm (8...