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Stefan Kren

Explore the profile of Stefan Kren including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 253
Followers 0
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Recent Articles
1.
Garry M, Kren S, Wenger J, Garry D
Stem Cells Dev . 2021 Apr; 30(14):697-704. PMID: 33843275
The ability to maintain viable cultures of mature, primary cardiomyocytes is challenging. The lack of viable cardiomyocyte cultures severely limits in vitro biochemical assays, toxicology assays, drug screening assays, and...
2.
Maeng G, Das S, Greising S, Gong W, Singh B, Kren S, et al.
Nat Biomed Eng . 2021 Mar; 5(8):805-814. PMID: 33782573
Because post-mortem human skeletal muscle is not viable, autologous muscle grafts are typically required in tissue reconstruction after muscle loss due to disease or injury. However, the use of autologous...
3.
Das S, Koyano-Nakagawa N, Gafni O, Maeng G, Singh B, Rasmussen T, et al.
Nat Biotechnol . 2020 Feb; 38(3):297-302. PMID: 32094659
The scarcity of donor organs may be addressed in the future by using pigs to grow humanized organs with lower potential for immunological rejection after transplantation in humans. Previous studies...
4.
Groehler 4th A, Kren S, Li Q, Robledo-Villafane M, Schmidt J, Garry M, et al.
Free Radic Biol Med . 2018 Mar; 120:89-101. PMID: 29540307
Myocardial infarction (MI) is a life-threatening condition that can occur when blood flow to the heart is interrupted due to a blockage in one or more of the coronary vessels....
5.
Syedain Z, Bradee A, Kren S, Taylor D, Tranquillo R
Tissue Eng Part A . 2012 Oct; 19(5-6):759-69. PMID: 23088577
Tissue-engineered heart valves (TEHV) have been proposed as a promising solution for the clinical needs of pediatric patients. In vivo studies have shown TEHV leaflet contraction and regurgitation after several...
6.
Gupta S, Verfaillie C, Chmielewski D, Kren S, Eidman K, Connaire J, et al.
J Am Soc Nephrol . 2006 Sep; 17(11):3028-40. PMID: 16988061
Acute kidney injury is followed by regeneration of damaged renal tubular epithelial cells. The purpose of this study was to test the hypothesis that renal stem cells exist in the...
7.
Juknevicius I, Segal Y, Kren S, Lee R, Hostetter T
Am J Physiol Renal Physiol . 2004 May; 286(6):F1059-62. PMID: 15130897
Aldosterone participates in the pathophysiology of several models of progressive chronic renal disease. Because of the causal connection between transforming growth factor-beta(1) (TGF-beta) and scarring in many such models, we...
8.
OBryan T, Weiher H, Rennke H, Kren S, Hostetter T
J Am Soc Nephrol . 2000 May; 11(6):1067-1074. PMID: 10820170
The mutant Mpv17 mouse is a transgenic strain that fails to express a protein that is normally expressed in the kidney and that is associated with peroxisomes. The present studies...