Stefan Goser
Overview
Explore the profile of Stefan Goser including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
338
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Recent Articles
1.
Bangert A, Andrassy M, Muller A, Bockstahler M, Fischer A, Volz C, et al.
Proc Natl Acad Sci U S A
. 2015 Dec;
113(2):E155-64.
PMID: 26715748
Autoimmune response to cardiac troponin I (TnI) induces inflammation and fibrosis in the myocardium. High-mobility group box 1 (HMGB1) is a multifunctional protein that exerts proinflammatory activity by mainly binding...
2.
Volz H, Buss S, Li J, Goser S, Andrassy M, Ottl R, et al.
Eur J Heart Fail
. 2011 Aug;
13(10):1052-9.
PMID: 21816762
Aims: Autoimmunity against cardiac troponin I (cTnI) has deleterious effects on the infarcted myocardium early after onset of ischaemia. Here, we explored the impact of cTnI-autoimmunity in the long term....
3.
Li J, Goser S, Leuschner F, Volz H, Buss S, Andrassy M, et al.
Int J Cardiol
. 2011 Jun;
162(3):245-52.
PMID: 21684025
Background: Antigen-specific therapy is a compelling approach for the treatment of autoimmune conditions. Primary goal is to induce the specific tolerization of self-reactive immune cells without altering host immunity against...
4.
Leib C, Goser S, Luthje D, Ottl R, Tretter T, Lasitschka F, et al.
Circ Res
. 2011 May;
109(2):130-40.
PMID: 21597011
Rationale: This study was performed to gain insights into novel therapeutic approaches for the treatment of autoimmune myocarditis. Objective: Chemical stimulation of the efferent arm of the vagus nerve through...
5.
Kaya Z, Leib C, Werfel S, Goser S, Ottl R, Leuchs B, et al.
Cardiovasc Res
. 2011 Mar;
91(1):116-23.
PMID: 21354997
Aims: Overexpression of therapeutic genes with potential disease-limiting effects, specifically at the site of inflammation, remains a major clinical challenge. In this study, we investigate the potential of adeno-associated virus...
6.
Kaya Z, Goser S, Buss S, Leuschner F, Ottl R, Li J, et al.
Circulation
. 2008 Oct;
118(20):2063-72.
PMID: 18955666
Background: Despite the widespread use of cardiac troponins for diagnosis of myocyte injury and risk stratification in acute cardiac disorders, little is known about the long-term effects of the released...
7.
Leuschner F, Li J, Goser S, Reinhardt L, Ottl R, Bride P, et al.
Eur Heart J
. 2008 Jun;
29(16):1949-55.
PMID: 18556712
Aims: Application of antibodies against cardiac troponin I (cTnI-Ab) can induce dilation and dysfunction of the heart in mice. Recently, we demonstrated that immunization with cTnI induces inflammation and fibrosis...
8.
Goser S, Andrassy M, Buss S, Leuschner F, Volz C, Ottl R, et al.
Circulation
. 2006 Oct;
114(16):1693-702.
PMID: 17015788
Background: Cardiac troponins in blood are the most preferred markers of myocardial damage. The fact that they are normally not found in the circulation provides a high level of clinical...
9.
Goser S, Ottl R, Brodner A, Dengler T, Torzewski J, Egashira K, et al.
Circulation
. 2005 Dec;
112(22):3400-7.
PMID: 16316965
Background: Autoimmune myocarditis is a principal cause of heart failure among young adults and is often a precursor of dilated cardiomyopathy. Monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-1alpha (MIP-1alpha)...