Stefan Ebert
Overview
Explore the profile of Stefan Ebert including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
17
Citations
428
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0
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Recent Articles
1.
Ebert S, Bohm V, Buttner J, Brune W, Brinkmann M, Holtappels R, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1012173.
PMID: 39146364
CD8 T cells are the predominant effector cells of adaptive immunity in preventing cytomegalovirus (CMV) multiple-organ disease caused by cytopathogenic tissue infection. The mechanism by which CMV-specific, naïve CD8 T...
2.
Di Matteo S, Munari E, Fiore P, Santopolo S, Sampaoli C, Pelosi A, et al.
Front Immunol
. 2023 Jun;
14:1183668.
PMID: 37334356
Background: Melanoma is a lethal skin cancer, and the risk of developing it is increased by exposure to ultraviolet (UV) radiation. The production of cytokines such as interleukin-15 (IL-15), induced...
3.
Nava Lauson C, Tiberti S, Corsetto P, Conte F, Tyagi P, Machwirth M, et al.
Cell Metab
. 2023 Mar;
35(4):633-650.e9.
PMID: 36898381
The metabolic state represents a major hurdle for an effective adoptive T cell therapy (ACT). Indeed, specific lipids can harm CD8 T cell (CTL) mitochondrial integrity, leading to defective antitumor...
4.
Pediatric Tumors-Mediated Inhibitory Effect on NK Cells: The Case of Neuroblastoma and Wilms' Tumors
Pelosi A, Fiore P, Di Matteo S, Veneziani I, Caruana I, Ebert S, et al.
Cancers (Basel)
. 2021 Jun;
13(10).
PMID: 34069127
Natural killer (NK) cells play a key role in the control of cancer development, progression and metastatic dissemination. However, tumor cells develop an array of strategies capable of impairing the...
5.
Stein R, Ebert S, Schlahsa L, Scholz C, Braun M, Hauck P, et al.
Cancer Res
. 2019 Jan;
79(7):1507-1519.
PMID: 30692216
Targeting of tumor immune escape mechanisms holds enormous therapeutic potential. Still, most patients progress under immune checkpoint blockade and some even become hyperprogressors. To investigate how cancer cells respond to...
6.
Holtappels R, Lemmermann N, Podlech J, Ebert S, Reddehase M
Front Immunol
. 2016 Jul;
7:232.
PMID: 27379095
Successful reconstitution of cytomegalovirus (CMV)-specific CD8(+) T cells by hematopoietic cell transplantation (HCT) gives a favorable prognosis for the control of CMV reactivation and prevention of CMV disease after hematoablative...
7.
Fink A, Blaum F, Babic Cac M, Ebert S, Lemmermann N, Reddehase M
Med Microbiol Immunol
. 2015 Apr;
204(3):383-94.
PMID: 25850989
Viruses have evolved proteins that bind immunologically relevant cargo molecules at the cell surface for their downmodulation by internalization. Via a tyrosine-based sorting motif YXXΦ in their cytoplasmic tails, they...
8.
Podlech J, Ebert S, Becker M, Reddehase M, Stassen M, Lemmermann N
Med Microbiol Immunol
. 2015 Feb;
204(3):327-34.
PMID: 25648117
Reactivation of latent cytomegalovirus (CMV) in the transient immunocompromised state after hematoablative treatment is a major concern in patients undergoing hematopoietic cell transplantation (HCT) as a therapy of hematopoietic malignancies....
9.
Becker M, Lemmermann N, Ebert S, Baars P, Renzaho A, Podlech J, et al.
Cell Mol Immunol
. 2014 Aug;
12(2):192-201.
PMID: 25152077
The succinct metaphor, 'the immune system's loaded gun', has been used to describe the role of mast cells (MCs) due to their storage of a wide range of potent pro-inflammatory...
10.
Ebert S, Becker M, Lemmermann N, Buttner J, Michel A, Taube C, et al.
PLoS Pathog
. 2014 Apr;
10(4):e1004100.
PMID: 24763809
The lungs are a noted predilection site of acute, latent, and reactivated cytomegalovirus (CMV) infections. Interstitial pneumonia is the most dreaded manifestation of CMV disease in the immunocompromised host, whereas...