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Stefaan Verhulst

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Recent Articles
11.
Verhulst S, Vidal Bustamante C, Carvajal-Velez L, Cece F, Requejo J, Shaw A, et al.
J Adolesc Health . 2022 Aug; 72(1S):S20-S26. PMID: 35931647
Purpose: Existing datasets and research in the field of adolescent mental health do not always meet the needs of practitioners, policymakers, and program implementers, particularly in the context of vulnerable...
12.
Verhulst S, Young A
Front Big Data . 2022 Aug; 5:888384. PMID: 35923558
As a society, we need to become more sophisticated in assessing and addressing data asymmetries-and their resulting political and economic power inequalities-particularly in the realm of open science, research, and...
13.
Obermeier M, Vadolas J, Verhulst S, Goossens E, Baert Y
Front Cell Dev Biol . 2022 Jul; 10:891173. PMID: 35774227
Gene editing in male germline stem (GS) cells is a potent tool to study spermatogenesis and to create transgenic mice. Various engineered nucleases already demonstrated the ability to modify the...
14.
Vlummens P, Verhulst S, de Veirman K, Maes A, Menu E, Moreaux J, et al.
Front Cell Dev Biol . 2022 Jun; 10:879057. PMID: 35757005
Multiple myeloma (MM) is an incurable clonal plasma cell malignancy. Subsets of patients have high-risk features linked with dismal outcome. Therefore, the need for effective therapeutic options remains high. Here,...
15.
De Beck L, Awad R, Basso V, Casares N, De Ridder K, De Vlaeminck Y, et al.
Front Immunol . 2022 May; 13:799636. PMID: 35634329
Immunotherapy has improved the treatment of malignant skin cancer of the melanoma type, yet overall clinical response rates remain low. Combination therapies could be key to meet this cogent medical...
16.
De Ridder K, Locy H, Piccioni E, Zuazo M, Awad R, Verhulst S, et al.
Front Immunol . 2022 May; 13:811867. PMID: 35493461
Immune checkpoint blockade (ICB) of the PD-1 pathway revolutionized the survival forecast for advanced non-small cell lung cancer (NSCLC). Yet, the majority of PD-L1 NSCLC patients are refractory to anti-PD-L1...
17.
Dewyse L, De Smet V, Verhulst S, Eysackers N, Kunda R, Messaoudi N, et al.
Front Med (Lausanne) . 2022 Apr; 9:862185. PMID: 35433753
models of human liver disease often fail to mimic the complex 3D structures and cellular organizations found . Precision cut liver slices (PCLS) retain the complex physiological architecture of the...
18.
Locy H, Verhulst S, Cools W, Waelput W, Brock S, Cras L, et al.
Front Immunol . 2022 Feb; 13:794175. PMID: 35222378
Scoring of tumor-infiltrating lymphocytes (TILs) in breast cancer specimens has gained increasing attention, as TILs have prognostic and predictive value in HER2 and triple-negative breast cancer. We evaluated the intra-...
19.
De Smet V, Eysackers N, Merens V, Dastjerd M, Halder G, Verhulst S, et al.
Cell Death Dis . 2021 Nov; 12(12):1110. PMID: 34839349
Activated hepatic stellate cells (aHSC) are the main source of extra cellular matrix in liver fibrosis. Activation is classically divided in two phases: initiation and perpetuation. Currently, HSC-based therapeutic candidates...
20.
Verhulst S, van Os E, De Smet V, Eysackers N, Mannaerts I, van Grunsven L
Front Med (Lausanne) . 2021 Nov; 8:750044. PMID: 34746184
Liver sinusoidal endothelial cells have a gatekeeper function in liver homeostasis by permitting substrates from the bloodstream into the space of Disse and regulating hepatic stellate cell activation status. Maintenance...